Literature DB >> 2882773

No effects on sleep of a histamine H1-receptor antagonist: temelastine.

K Adam, I Oswald.   

Abstract

Twelve volunteer poor sleepers of mean age 57 years took placebo on each of 3 consecutive nights, and temelastine 100 mg on 3 consecutive nights in a double-blind balanced order study. Sleep in the EEG laboratory was unaffected by the drug.

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Year:  1986        PMID： 2882773      PMCID： PMC1401224          DOI： 10.1111/j.1365-2125.1986.tb02963.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  5 in total

1.  A repeated dose comparison of the side effects of five antihistamines on objective assessments of psychomotor performance, central nervous system arousal and subjective appraisals of sleep and early morning behaviour.

Authors:  I Hindmarch; A C Parrott
Journal:  Arzneimittelforschung       Date:  1978

2.  The hypnotic effects of an antihistamine: promethazine.

Authors:  K Adam; I Oswald
Journal:  Br J Clin Pharmacol       Date:  1986-12       Impact factor: 4.335

3.  Daytime sleepiness and antihistamines.

Authors:  T A Roehrs; E I Tietz; F J Zorick; T Roth
Journal:  Sleep       Date:  1984       Impact factor: 5.849

4.  Effects of two antihistamine drugs on actual driving performance.

Authors:  T Betts; D Markman; S Debenham; D Mortiboy; T McKevitt
Journal:  Br Med J (Clin Res Ed)       Date:  1984-01-28

5.  Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1-receptor antagonist with negligible ability to penetrate the central nervous system.

Authors:  E A Brown; R Griffiths; C A Harvey; D A Owen
Journal:  Br J Pharmacol       Date:  1986-03       Impact factor: 8.739
  5 in total

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