Tuba Talo Yildirim1, Filiz Acun Kaya2, Beran Yokus3, Mehmet Colak4, Eylem Ozdemir Kaya5, Giray Tekin6, Ebru Saribas2, Ersin Uysal7, Guliz N Guncu8. 1. a Department of Periodontology, Faculty of Dentistry , Firat University , Elazig , Turkey. 2. b Department of Periodontology, Faculty of Dentistry , Dicle University , Diyarbakir , Turkey. 3. c Department of Biochemistry, Faculty of Medicine, Dicle University , Diyarbakir , Turkey. 4. d Department of Dento-Maxillofacial Radiology, Faculty of Dentistry, Dicle University , Dicle University , Diyarbakir , Turkey. 5. e Mersin Mouth and Teeth Health Center , Mersin , Turkey. 6. f Diyarbakir Mouth and Teeth Health Center , Diyarbakir , Turkey. 7. g Department of Technics Programs , Diyarbakir Vocational High School, Dicle University , Diyarbakir , Turkey. 8. h Department of Periodontology, Faculty of Dentistry , Hacettepe University , Ankara , Turkey.
Abstract
OBJECTIVE: Dental implants have been widely and successfully used in recent years as an alternative treatment for removable and fixed dental prostheses. The aim of this randomized prospective study was to determine the alveolar bone loss rate (ABLR) and IL-1β levels in one- and two-stage surgical procedures. MATERIALS AND METHODS: This study included 40 patients with a single missing tooth in the posterior mandible; dental implants were inserted using a one-stage surgical procedure (Group I) or a two-stage surgical procedure (Group II). All clinical periodontal parameters were recorded; peri-implant crevicular fluid (PICF) samples were collected before loading (T0) and during the third (T1) and sixth (T2) months after loading. ABLR values were evaluated at T0 and T2 by using dental tomography. PICF was analysed after T2 samples were collected. The study was registered through clinicaltrials.gov; identifier NCT03045458. RESULTS: This study found that, the probing pocket depth was found to be significantly higher in Group I than Group II at both T1 and T2 (p < .05). There was no significant difference in other clinical parameters between the groups (p > .05). There was a significant difference between Group I ABLR values at T0 and T2 (p < .05). The PICF IL-1β levels were not significantly different between groups (p > .05). CONCLUSIONS: Within the limitations of the short observational period and small sample size of this study, two-stage implant placement shows comparable clinical outcomes to implants placed using a one-stage placement protocol.
RCT Entities:
OBJECTIVE: Dental implants have been widely and successfully used in recent years as an alternative treatment for removable and fixed dental prostheses. The aim of this randomized prospective study was to determine the alveolar bone loss rate (ABLR) and IL-1β levels in one- and two-stage surgical procedures. MATERIALS AND METHODS: This study included 40 patients with a single missing tooth in the posterior mandible; dental implants were inserted using a one-stage surgical procedure (Group I) or a two-stage surgical procedure (Group II). All clinical periodontal parameters were recorded; peri-implant crevicular fluid (PICF) samples were collected before loading (T0) and during the third (T1) and sixth (T2) months after loading. ABLR values were evaluated at T0 and T2 by using dental tomography. PICF was analysed after T2 samples were collected. The study was registered through clinicaltrials.gov; identifier NCT03045458. RESULTS: This study found that, the probing pocket depth was found to be significantly higher in Group I than Group II at both T1 and T2 (p < .05). There was no significant difference in other clinical parameters between the groups (p > .05). There was a significant difference between Group I ABLR values at T0 and T2 (p < .05). The PICF IL-1β levels were not significantly different between groups (p > .05). CONCLUSIONS: Within the limitations of the short observational period and small sample size of this study, two-stage implant placement shows comparable clinical outcomes to implants placed using a one-stage placement protocol.
Authors: Necla Asli Kocak-Oztug; Gamze Zeynep Adem-Siyli; Orkhan Abishev; Sule Batu; Yegane Guven; Ali Cekici; Aslan Y Gokbuget; Erhan Firatli; Serdar Cintan Journal: Biomed Res Int Date: 2022-05-21 Impact factor: 3.246