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Literature DB >> 28823964

MicroRNAs in prostate cancer: Functional role as biomarkers.

Rajnee Kanwal¹, Alexis R Plaga², Xiaoqi Liu³, Girish C Shukla², Sanjay Gupta⁴.

Abstract

MicroRNAs (miRNAs) are small endogenous non-coding molecules that alters gene expression through post-transcriptional regulation of messenger RNA. Compelling evidence suggest the role of miRNA in cancer biology having potential as diagnostic, prognostic and predictive biomarkers. This review summarizes the current knowledge on miRNA deregulated in prostate cancer and their role as oncogene, tumor suppressor and metastasis regulators. The emerging information elucidating the biological function of miRNA is promising and may lead to their potential usefulness as diagnostic/prognostic markers and development as effective therapeutic tools for management of prostate cancer.

Entities: Disease

Keywords: Androgen receptor; Biomarkers; Castrate-resistant prostate cancer; Non-coding RNA; Oncomirs; Tumor suppressor

Mesh：

Substances：

Year: 2017 PMID： 28823964 DOI： 10.1016/j.canlet.2017.08.011

Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679

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Cited

53 in total

Review 1. Regulation of breast cancer metastasis signaling by miRNAs.

Authors: Belinda J Petri; Carolyn M Klinge
Journal: Cancer Metastasis Rev Date: 2020-09 Impact factor: 9.264

2. Grape Powder Supplementation Attenuates Prostate Neoplasia Associated with Pten Haploinsufficiency in Mice Fed High-Fat Diet.

Authors: Tanvi Joshi; Ishani Patel; Avinash Kumar; Virginia Donovan; Anait S Levenson
Journal: Mol Nutr Food Res Date: 2020-07-12 Impact factor: 5.914

3. Bioinformatics Prediction and Analysis of MicroRNAs and Their Targets as Biomarkers for Prostate Cancer: A Preliminary Study.

Authors: Chipampe Patricia Lombe; Mervin Meyer; Ashley Pretorius
Journal: Mol Biotechnol Date: 2021-10-19 Impact factor: 2.695

4. Utilization of chromogenic enzyme substrates for signal amplification in multiplexed detection of biomolecules using surface mass spectrometry.

Authors: Hee-Kyung Na; Hyun Kyong Shon; Hye Young Son; Eunji Jang; Sunho Joh; Yong-Min Huh; David G Castner; Tae Geol Lee
Journal: Sens Actuators B Chem Date: 2021-01-15 Impact factor: 7.460

5. Association of Androgenic Regulation and MicroRNAs in Acinar Adenocarcinoma of Prostate.

Authors: Julio Guilherme Balieiro Bernardes; Marianne Rodrigues Fernandes; Juliana Carla Gomes Rodrigues; Lui Wallacy Morikawa Souza Vinagre; Lucas Favacho Pastana; Elizabeth Ayres Fragoso Dobbin; Jéssyca Amanda Gomes Medeiros; Leonidas Braga Dias Junior; Gabriel Monteiro Bernardes; Izabel Maria Monteiro Bernardes; Ney Pereira Carneiro Dos Santos; Samia Demachki; Rommel Mario Rodriguez Burbano
Journal: Genes (Basel) Date: 2022-03-30 Impact factor: 4.141

MicroRNAs in prostate cancer: Functional role as biomarkers.

Review 1. Regulation of breast cancer metastasis signaling by miRNAs.

2. Grape Powder Supplementation Attenuates Prostate Neoplasia Associated with Pten Haploinsufficiency in Mice Fed High-Fat Diet.

3. Bioinformatics Prediction and Analysis of MicroRNAs and Their Targets as Biomarkers for Prostate Cancer: A Preliminary Study.

4. Utilization of chromogenic enzyme substrates for signal amplification in multiplexed detection of biomolecules using surface mass spectrometry.

5. Association of Androgenic Regulation and MicroRNAs in Acinar Adenocarcinoma of Prostate.

6. Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients.

Review 7. Detection and Prognosis of Prostate Cancer Using Blood-Based Biomarkers.

8. MicroRNA panel in serum reveals novel diagnostic biomarkers for prostate cancer.

9. An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer.

10. miR-593-3p Promotes Proliferation and Invasion in Prostate Cancer Cells by Targeting ADIPOR1.