| Literature DB >> 28822599 |
Joanna K L Wong1, Rashin Mohseni2, Amir Ali Hamidieh2, Robert E MacLaren3, Nagy Habib4, Alexander M Seifalian5.
Abstract
Organic nanoparticle-based (ONP) gene therapy is a potential strategy to cure human cancer. However, there are still many practical barriers before the promising results from in vitro and preclinical studies can be translated to clinical success. We discuss the reasons behind the hesitant uptake by the clinic.Entities:
Keywords: clinical trials; gene therapy; limitations; organic nanoparticle
Mesh：
Year: 2017 PMID： 28822599 DOI： 10.1016/j.tibtech.2017.07.009
Source DB: PubMed Journal: Trends Biotechnol ISSN： 0167-7799 Impact factor: 19.536