Literature DB >> 2882180

Effect of 13-cis-retinoic acid on survival of patients with myelodysplastic syndrome.

R E Clark, A Jacobs, C J Lush, S A Smith.   

Abstract

A randomised therapeutic trial of 13-cis-retinoic acid was carried out in 70 patients with myelodysplastic syndrome having 5% or fewer marrow blast cells. Among non-sideroblastic patients the 1-year survival in the treated group was 77%, compared with 36% in the control group. There were too few deaths among patients with sideroblastic anaemia to allow any effect of therapy on survival to be evaluated.

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Year:  1987        PMID: 2882180     DOI: 10.1016/s0140-6736(87)92796-6

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  4 in total

Review 1.  Acute myelogenous leukaemia in children.

Authors:  S O Lie
Journal:  Eur J Pediatr       Date:  1989-02       Impact factor: 3.183

2.  The myelodysplastic syndromes.

Authors:  A Jacobs
Journal:  Br Med J (Clin Res Ed)       Date:  1987-08-29

Review 3.  Myelodysplastic syndromes.

Authors:  D C Doll; A F List
Journal:  West J Med       Date:  1989-08

4.  Development of resistance to nalidixic acid and the fluoroquinolones after the introduction of norfloxacin and ofloxacin.

Authors:  M Kresken; B Wiedemann
Journal:  Antimicrob Agents Chemother       Date:  1988-08       Impact factor: 5.191

  4 in total

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