Literature DB >> 28820714

Epidemiology of Cutaneous Leishmaniasis in a Colombian Municipality.

Diego Alejandro Medina-Morales1, Manuel E Machado-Duque1, Jorge Enrique Machado-Alba1.   

Abstract

This study describes the epidemiological and clinical characteristics of leishmaniasis and the pharmacological treatment of this disease in the municipality of Pueblo Rico, Risaralda, between January 2010 and December 2014. An observational study was conducted using information from the clinical records and epidemiological reports of patients diagnosed and confirmed with leishmaniasis of any age and sex, including sociodemographic, clinical, and pharmacological variables of the therapy received. Univariate and bivariate analyses were performed. A total of 539 cases of leishmaniasis were confirmed, with 29.5% occurring in children under 5 years of age. The median age was 10 years, with predominance in males (55.5%). The indigenous Emberá (aboriginal Americans) were the most affected (50.8%), and 93.3% of cases occurred in people living in scattered rural areas. All lesions corresponded to cutaneous leishmaniasis, of which 251 patients had compromise of the upper limbs (46.6%), 221 of the face (41.0%), and 139 of the lower limbs (25.8%). Pentavalent antimony salts (n-methyl glucamine and sodium stibogluconate) were prescribed in 77.6% (N = 418) of the cases; miltefosine was the second most frequently prescribed medication (21.5%, N = 116). The inhabitants of rural areas and the indigenous communities are at a higher risk of acquiring the infection, particularly among infants, which highlights the importance of the biological, social, and demographic factors involved in the disease. There is a need to seek effective public health actions and further research this disease.

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Year:  2017        PMID: 28820714      PMCID: PMC5817762          DOI: 10.4269/ajtmh.17-0233

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  18 in total

1.  Distribution and etiology of leishmaniasis in Colombia.

Authors:  A Corredor; R D Kreutzer; R B Tesh; J Boshell; M T Palau; E Caceres; S Duque; D Pelaez; G Rodriguez; S Nichols
Journal:  Am J Trop Med Hyg       Date:  1990-03       Impact factor: 2.345

Review 2.  An update on pharmacotherapy for leishmaniasis.

Authors:  Shyam Sundar; Jaya Chakravarty
Journal:  Expert Opin Pharmacother       Date:  2014-10-25       Impact factor: 3.889

3.  Study of the scientific production on leishmaniasis in Latin America.

Authors:  Yuliana Perilla-Gonzalez; Daniela Gomez-Suta; Nathalia Delgado-Osorio; Natalia Hurtado-Hurtado; Juan D Baquero-Rodriguez; Andres F Lopez-Isaza; Guillermo J Lagos-Grisales; Soraya Villegas; Alfonso J Rodriguez-Morales
Journal:  Recent Pat Antiinfect Drug Discov       Date:  2014

Review 4.  Leishmaniasis.

Authors:  Lukasz Kedzierski
Journal:  Hum Vaccin       Date:  2011-11-01

Review 5.  The epidemiology and control of leishmaniasis in Andean countries.

Authors:  C R Davies; R Reithinger; D Campbell-Lendrum; D Feliciangeli; R Borges; N Rodriguez
Journal:  Cad Saude Publica       Date:  2000 Oct-Dec       Impact factor: 1.632

6.  Pharmacokinetics of antimony in children treated for leishmaniasis with meglumine antimoniate.

Authors:  Adriana Cruz; Petrie M Rainey; Barbara L Herwaldt; Grazia Stagni; Ricardo Palacios; Rodolfo Trujillo; Nancy G Saravia
Journal:  J Infect Dis       Date:  2007-01-11       Impact factor: 5.226

Review 7.  Cutaneous leishmaniasis.

Authors:  Richard Reithinger; Jean-Claude Dujardin; Hechmi Louzir; Claude Pirmez; Bruce Alexander; Simon Brooker
Journal:  Lancet Infect Dis       Date:  2007-09       Impact factor: 25.071

8.  Assessing epidemiology of cutaneous leishmaniasis in Isfahan, Iran.

Authors:  Marziyeh Karami; Monir Doudi; Mahbubeh Setorki
Journal:  J Vector Borne Dis       Date:  2013-03       Impact factor: 1.688

Review 9.  Leishmaniasis.

Authors:  Tonio V Piscopo; Charles Mallia Azzopardi
Journal:  Postgrad Med J       Date:  2007-02       Impact factor: 2.401

10.  Leishmaniasis worldwide and global estimates of its incidence.

Authors:  Jorge Alvar; Iván D Vélez; Caryn Bern; Mercé Herrero; Philippe Desjeux; Jorge Cano; Jean Jannin; Margriet den Boer
Journal:  PLoS One       Date:  2012-05-31       Impact factor: 3.240

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  2 in total

1.  Clinical and epidemiological profiles of patients with American cutaneous leishmaniasis from the states of Pernambuco and Amazonas, Brazil.

Authors:  Maria Gabriella Nunes de Melo; Rayana Carla Silva de Morais; Tayná Correia de Goes; Rômulo Pessoa E Silva; Rômulo Freire de Morais; Jorge Augusto de Oliveira Guerra; Maria Edileuza Felinto de Brito; Sinval Pinto Brandão Filho; Milena de Paiva Cavalcanti
Journal:  Rev Soc Bras Med Trop       Date:  2020-11-25       Impact factor: 1.581

2.  Gender and Cutaneous Leishmaniasis in Israel.

Authors:  Michal Solomon; Inbal Fuchs; Yael Glazer; Eli Schwartz
Journal:  Trop Med Infect Dis       Date:  2022-08-12
  2 in total

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