WenHua Yang1,2, Liang Jiang3, XiaoGuang Liu1, Feng Wei1, Miao Yu1, FengLiang Wu1, Lei Dang1, Hua Zhou1, Hua Zhang4, ZhongJun Liu5. 1. Orthopaedic Department, Peking University Third Hospital, No. 49 North Garden Road, HaiDian District, Beijing, 100191, China. 2. Emergency Department, Beijing Shijitan Hospital, Capital Medical University, No. 10 TieYi Road, Yangfangdian, HaiDian District, Beijing, 100038, China. 3. Orthopaedic Department, Peking University Third Hospital, No. 49 North Garden Road, HaiDian District, Beijing, 100191, China. jiangliang@bjmu.edu.cn. 4. Research Center of Clinical Epidemiology, Peking University Third Hospital, No. 49 North Garden Road, HaiDian District, Beijing, 100191, China. 5. Orthopaedic Department, Peking University Third Hospital, No. 49 North Garden Road, HaiDian District, Beijing, 100191, China. zjliu@bjmu.edu.cn.
Abstract
PURPOSE: To assess the safety of surgical intervention for extraspinal tumors in the cervical spine. METHODS: 110 consecutive patients were enrolled and followed-up at least 12 months or until death. The complication rates and risk factors were documented and analyzed. RESULTS: The quality of life in the surviving patients was significantly improved. The overall local recurrence rate was 17.3%. Twenty percent of patients developed distant metastasis. The perioperative mortality rate (30 days after surgery) was 0.9%. The complication related mortality was 1.8%. The rates of overall complication and major complication were 41.8% and 20.9%, respectively. The independent predictors for overall complications were Karnofsky score <60, multisegmental resection, and operation time >3 h. The independent predictors of major complications were comorbidity, tumor location at C1-C2, and combined approach. CONCLUSIONS: Surgery for cervical spine tumor could improve the quality of life, though it might be accompanied with high morbidity and mortality. It is a highly demanding procedure; however, it can be performed to an acceptable degree of safety.
PURPOSE: To assess the safety of surgical intervention for extraspinal tumors in the cervical spine. METHODS: 110 consecutive patients were enrolled and followed-up at least 12 months or until death. The complication rates and risk factors were documented and analyzed. RESULTS: The quality of life in the surviving patients was significantly improved. The overall local recurrence rate was 17.3%. Twenty percent of patients developed distant metastasis. The perioperative mortality rate (30 days after surgery) was 0.9%. The complication related mortality was 1.8%. The rates of overall complication and major complication were 41.8% and 20.9%, respectively. The independent predictors for overall complications were Karnofsky score <60, multisegmental resection, and operation time >3 h. The independent predictors of major complications were comorbidity, tumor location at C1-C2, and combined approach. CONCLUSIONS: Surgery for cervical spine tumor could improve the quality of life, though it might be accompanied with high morbidity and mortality. It is a highly demanding procedure; however, it can be performed to an acceptable degree of safety.
Entities:
Keywords:
Cervical; Complication; Mortality; Spine tumor; Surgery
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