Literature DB >> 28819839

A Novel Microfluidic Device for Isolation of Circulating Tumor Cells from Pancreatic Cancer Blood Samples.

Jose I Varillas1, Kangfu Chen2, Jinling Zhang2, Thomas J George3, Z Hugh Fan4,5.   

Abstract

Enumeration of circulating tumor cells (CTCs) can provide valuable prognostic information to guide cancer treatment as well as help monitor disease progression. Analysis of these rare malignant cells has the potential to further our understanding of cancer metastasis by gaining insights into CTC characteristics and properties. Microfluidics presents a unique platform to isolate and study CTCs. In this chapter, we describe the detailed procedures for the fabrication and use of a microfluidic device to detect CTCs from the blood of pancreatic cancer patients.

Entities:  

Keywords:  Circulating tumor cells; Microfluidics; Pancreatic cancer

Mesh：

Substances：

Year:  2017        PMID： 28819839      PMCID： PMC6509048          DOI： 10.1007/978-1-4939-7144-2_3

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  7 in total

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Authors:  Abraham D Stroock; Stephan K W Dertinger; Armand Ajdari; Igor Mezic; Howard A Stone; George M Whitesides
Journal:  Science       Date:  2002-01-25       Impact factor: 47.728

2.  Engineering and analysis of surface interactions in a microfluidic herringbone micromixer.

Authors:  Thomas P Forbes; Jason G Kralj
Journal:  Lab Chip       Date:  2012-06-15       Impact factor: 6.799

3.  Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system.

Authors:  Sabine Riethdorf; Herbert Fritsche; Volkmar Müller; Thomas Rau; Christian Schindlbeck; Brigitte Rack; Wolfgang Janni; Cornelia Coith; Katrin Beck; Fritz Jänicke; Summer Jackson; Terrie Gornet; Massimo Cristofanilli; Klaus Pantel
Journal:  Clin Cancer Res       Date:  2007-02-01       Impact factor: 12.531

4.  Isolation of circulating tumor cells using a microvortex-generating herringbone-chip.

Authors:  Shannon L Stott; Chia-Hsien Hsu; Dina I Tsukrov; Min Yu; David T Miyamoto; Belinda A Waltman; S Michael Rothenberg; Ajay M Shah; Malgorzata E Smas; George K Korir; Frederick P Floyd; Anna J Gilman; Jenna B Lord; Daniel Winokur; Simeon Springer; Daniel Irimia; Sunitha Nagrath; Lecia V Sequist; Richard J Lee; Kurt J Isselbacher; Shyamala Maheswaran; Daniel A Haber; Mehmet Toner
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-07       Impact factor: 11.205

5.  Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip.

Authors:  Weian Sheng; Olorunseun O Ogunwobi; Tao Chen; Jinling Zhang; Thomas J George; Chen Liu; Z Hugh Fan
Journal:  Lab Chip       Date:  2013-11-13       Impact factor: 6.799

Review 6.  Circulating tumor cells: approaches to isolation and characterization.

Authors:  Min Yu; Shannon Stott; Mehmet Toner; Shyamala Maheswaran; Daniel A Haber
Journal:  J Cell Biol       Date:  2011-02-07       Impact factor: 10.539

7.  Isolation and retrieval of circulating tumor cells using centrifugal forces.

Authors:  Han Wei Hou; Majid Ebrahimi Warkiani; Bee Luan Khoo; Zi Rui Li; Ross A Soo; Daniel Shao-Weng Tan; Wan-Teck Lim; Jongyoon Han; Ali Asgar S Bhagat; Chwee Teck Lim
Journal:  Sci Rep       Date:  2013-02-12       Impact factor: 4.379
  7 in total
  3 in total

1.  Microfluidic Isolation of Circulating Tumor Cells and Cancer Stem-Like Cells from Patients with Pancreatic Ductal Adenocarcinoma.

Authors:  Jose I Varillas; Jinling Zhang; Kangfu Chen; Isis I Barnes; Chen Liu; Thomas J George; Z Hugh Fan
Journal:  Theranostics       Date:  2019-02-20       Impact factor: 11.556

Review 2.  Liquid biopsy in pancreatic ductal adenocarcinoma: current status of circulating tumor cells and circulating tumor DNA.

Authors:  Jee-Soo Lee; Sung Sup Park; Young Kyung Lee; Jeffrey A Norton; Stefanie S Jeffrey
Journal:  Mol Oncol       Date:  2019-07-30       Impact factor: 6.603

3.  Using a combination of gangliosides and cell surface vimentin as surface biomarkers for isolating osteosarcoma cells in microfluidic devices.

Authors:  Henrietta O Fasanya; Pablo J Dopico; Zachary Yeager; Z Hugh Fan; Dietmar W Siemann
Journal:  J Bone Oncol       Date:  2021-03-24       Impact factor: 4.491
  3 in total

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