| Literature DB >> 2881903 |
R A Gibbs, J Camakaris, G S Hodgson, R F Martin.
Abstract
The predominant initial lesion induced by 125I decay in DNa is a double-strand DNA break comprising a 'mini deletion' of up to several base pairs (bp). However, Southern analysis of the structure of 125I decay-induced HPRT mutants in Chinese hamster ovary cells revealed that most of the mutants are deletions of thousands of bps. A similar predominance of substantial deletions was also found in X-ray-induced mutants.Entities:
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Year: 1987 PMID： 2881903 DOI： 10.1080/09553008714550691
Source DB: PubMed Journal: Int J Radiat Biol Relat Stud Phys Chem Med ISSN： 0020-7616