Literature DB >> 28817698

Correction: Enhanced Hepatogenic Transdifferentiation of Human Adipose Tissue Mesenchymal Stem Cells by Gene Engineering with Oct4 and Sox2.

Sei-Myoung Han, Ye-Rin Coh, Jin-Ok Ahn, Goo Jang, Soo Young Yum, Sung-Keun Kang, Hee-Woo Lee, Hwa-Young Youn.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0108874.].

Entities:  

Year:  2017        PMID: 28817698      PMCID: PMC5560703          DOI: 10.1371/journal.pone.0183734

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


In the graph legend in Panel A of Fig 4, the color for RFP-ATMSCs is incorrect. Please see the corrected Fig 4 here.
Fig 4

PCR analysis and immunofluorescence of liver markers after 28 days hepatogenic differentiation.

(A) The mRNA expression level of albumin (ALB) was strongly expressed in hepatogenically differentiated Oct4/Sox2-ATMSCs, whereas the expression level of α-fetoprotein (AFP) was lower than that of RFP-ATMSCs. The expression levels of transferrin were not significantly different in both cells. Undifferentiated ATMSCs and HepG2 were used as negative and positive controls, respectively. (B) Hepatocyte-like cells from RFP- and Oct4/Sox2-ATMSCs are confirmed by immunofluorescence staining for AFP and ALB. Nuclei were counterstained with Hoecst33342.

PCR analysis and immunofluorescence of liver markers after 28 days hepatogenic differentiation.

(A) The mRNA expression level of albumin (ALB) was strongly expressed in hepatogenically differentiated Oct4/Sox2-ATMSCs, whereas the expression level of α-fetoprotein (AFP) was lower than that of RFP-ATMSCs. The expression levels of transferrin were not significantly different in both cells. Undifferentiated ATMSCs and HepG2 were used as negative and positive controls, respectively. (B) Hepatocyte-like cells from RFP- and Oct4/Sox2-ATMSCs are confirmed by immunofluorescence staining for AFP and ALB. Nuclei were counterstained with Hoecst33342.
  1 in total

1.  Enhanced hepatogenic transdifferentiation of human adipose tissue mesenchymal stem cells by gene engineering with Oct4 and Sox2.

Authors:  Sei-Myoung Han; Ye-Rin Coh; Jin-Ok Ahn; Goo Jang; Soo Young Yum; Sung-Keun Kang; Hee-Woo Lee; Hwa-Young Youn
Journal:  PLoS One       Date:  2015-03-27       Impact factor: 3.240

  1 in total
  1 in total

1.  Molecular characterization of AwSox2 from bivalve Anodonta woodiana: Elucidating its player in the immune response.

Authors:  Xichao Xia; Cuiui Guan; Jiawei Chen; Maolin Qiu; Jinxu Qi; Mengwei Wei; Xiaowei Wang; Ke Zhang; Suxiang Lu; Linguo Zhang; Chunxiu Hua; Shipeng Xue; Lunguang Yao
Journal:  Innate Immun       Date:  2019-12-31       Impact factor: 2.680

  1 in total

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