Literature DB >> 2881691

Reduced noradrenaline turnover in brown adipose tissue of lactating rats.

F Villarroya, A Felipe, T Mampel.   

Abstract

Brown adipose tissue properties as well as noradrenaline turnover in the tissue were determined in 15-day lactating rats and virgin controls. Brown adipose tissue thermogenic activity was reduced in lactating rats as shown by a decrease in weight, cytochrome oxidase activity and mitochondrial GDP-binding. The noradrenaline turnover rate was lower in brown adipose tissue from lactating rats. It is suggested that diminished sympathetic activity in brown adipose tissue may be a major cause of the reduced tissue thermogenic activity during lactation.

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Year:  1987        PMID: 2881691     DOI: 10.1016/0300-9629(87)90529-9

Source DB:  PubMed          Journal:  Comp Biochem Physiol A Comp Physiol        ISSN: 0300-9629


  7 in total

1.  Inactivation of brown adipose tissue thermogenesis by oestradiol treatment in cold-acclimated rats.

Authors:  M L Puerta; M P Nava; M Abelenda; A Fernández
Journal:  Pflugers Arch       Date:  1990-08       Impact factor: 3.657

2.  Functional atrophy of brown adipose tissue during lactation in mice. Effects of lactation and weaning on mitochondrial GDP binding and uncoupling protein.

Authors:  P Trayhurn; G Jennings
Journal:  Biochem J       Date:  1987-11-15       Impact factor: 3.857

3.  Insulin resistance of glucose metabolism in isolated brown adipocytes of lactating rats. Evidence for a post-receptor defect in insulin action.

Authors:  A F Burnol; S Ebner; J Kandé; J Girard
Journal:  Biochem J       Date:  1990-01-15       Impact factor: 3.857

4.  Iodothyronine 5'-deiodinase activity and thyroid hormone content in brown adipose tissue during the breeding cycle of the rat.

Authors:  O Viñas; M Giralt; M J Obregón; R Iglesias; F Villarroya; T Mampel
Journal:  Biochem J       Date:  1988-10-15       Impact factor: 3.857

5.  Differential regulation of expression of genes encoding uncoupling proteins 2 and 3 in brown adipose tissue during lactation in mice.

Authors:  N Pedraza; G Solanes; R Iglesias; M Vázquez; M Giralt; F Villarroya
Journal:  Biochem J       Date:  2001-04-01       Impact factor: 3.857

6.  Co-ordinate decrease in the expression of the mitochondrial genome and nuclear genes for mitochondrial proteins in the lactation-induced mitochondrial hypotrophy of rat brown fat.

Authors:  I Martin; M Giralt; O Viñas; R Iglesias; T Mampel; F Villarroya
Journal:  Biochem J       Date:  1995-06-15       Impact factor: 3.857

7.  Adaptative decrease in expression of the mRNA for uncoupling protein and subunit II of cytochrome c oxidase in rat brown adipose tissue during pregnancy and lactation.

Authors:  I Martin; M Giralt; O Viñas; R Iglesias; T Mampel; F Villarroya
Journal:  Biochem J       Date:  1989-11-01       Impact factor: 3.857

  7 in total

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