| Literature DB >> 28816049 |
Marvin Lübcke1,2, Weiming Yuan1, Kálmán J Szabó1,2.
Abstract
A new Rh-catalyzed, three-component reaction for the oxytrifluoromethylthiolation of α-diazoketones was developed. The SCF3 functionality was introduced using a stable dibenzenesulfonimide reagent under mild conditions. Alcohols, acetals, and ethers were used as the alkoxy sources. Cyclic ethers underwent a trifunctionalization reaction through the introduction of SCF3, OR, and N(SO2Ph)2 substituents in a single step.Entities:
Year: 2017 PMID： 28816049 DOI： 10.1021/acs.orglett.7b02139
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005