Richard Justin Garling1, Rasanjeet Singh2, Carolyn Harris3,4, Abilash Haridas3,5. 1. Department of Neurosurgery, Wayne State University, 4201 St. Antoine blvd, Suite 6E, Neurosurgery, Detroit, MI, 48201, USA. Jgarling@med.wayne.edu. 2. Wayne State University School of Medicine, Detroit, MI, USA. 3. Department of Neurosurgery, Wayne State University, 4201 St. Antoine blvd, Suite 6E, Neurosurgery, Detroit, MI, 48201, USA. 4. Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA. 5. Department of Neurosurgery, Children's Hospital of Michigan, Detroit, MI, USA.
Abstract
BACKGROUND: Rhabdoid tumors are highly malignant tumors predominantly affecting the pediatric population. When these tumors occur outside of the kidneys, they are referred to as malignant extrarenal rhabdoid tumors (MERT), a rare highly aggressive subtype. Less commonly, these tumors involve the neuro-axis. OBJECTIVE: Here we present a case of a 15-year-old girl with intradural MERT of the lumbosacral spine who presented with back pain, sudden worsening of lower extremity strength, and complete loss of bowel and bladder control. RESULTS: The patient's tumor showed loss of INI-1 and negative staining for cytokeratin AE1AE3, CD99, and SOX10. CONCLUSIONS: To our knowledge, there are no previous case reports of MERT with intradural lumbosacral spinal involvement.
BACKGROUND:Rhabdoid tumors are highly malignant tumors predominantly affecting the pediatric population. When these tumors occur outside of the kidneys, they are referred to as malignant extrarenal rhabdoid tumors (MERT), a rare highly aggressive subtype. Less commonly, these tumors involve the neuro-axis. OBJECTIVE: Here we present a case of a 15-year-old girl with intradural MERT of the lumbosacral spine who presented with back pain, sudden worsening of lower extremity strength, and complete loss of bowel and bladder control. RESULTS: The patient's tumor showed loss of INI-1 and negative staining for cytokeratin AE1AE3, CD99, and SOX10. CONCLUSIONS: To our knowledge, there are no previous case reports of MERT with intradural lumbosacral spinal involvement.
Authors: Jared S Fridley; Roukoz B Chamoun; William E Whitehead; Daniel J Curry; Thomas G Luerssen; Adekunle Adesina; Andrew Jea Journal: Pediatr Neurosurg Date: 2009-06-15 Impact factor: 1.162