Raissa Carla Moreira1, Marise Bueno Zonta2, Ana Paula Serra de Araújo3, Vera Lúcia Israel4, Hélio A G Teive5. 1. Universidade Federal do Paraná, Curitiba PR, Brasil. 2. Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Reabilitação, Curitiba PR, Brasil. 3. Secretaria Municipal de Saúde, Prefeitura Municipal de Guarapuava, Guarapuava PR, Brasil. 4. Universidade Federal do Paraná, Departamento de Fisioterapia, Curitiba PR, Brasil. 5. Universidade Federal do Paraná, Departamento de Medicina, Curitiba PR, Brasil.
Abstract
OBJECTIVE: To investigate which factors are associated with the quality of life decline in Parkinson's disease patients from mild to moderate stages. METHODS: The Unified Parkinson's Disease Rating Scale and Parkinson's Disease Questionnaire-39 were used to evaluate clinical/functional data and the quality of life. RESULTS: The markers of clinical/functional worsening were drooling (p < 0.004), need for assistance with hygiene (p = 0.02), greater freezing frequency (p = 0.042), bradykinesia (p = 0.031), greater intensity of the resting tremor (p = 0.035) and "pill rolling" (p = 0.001). The decline in quality of life was related to stigma (p = 0.043), greater impairment in cognition (p = 0.002), mobility (p = 0.013) and for daily living activities (p = 0.05), and was considered more significant in men, married, older individuals, and those with a longer time of disease. CONCLUSIONS: The quality of life worsening markers at the moderate stage were related to stigma, worsening of cognition, and to greater impairment in mobility and daily living activities.
OBJECTIVE: To investigate which factors are associated with the quality of life decline in Parkinson's disease patients from mild to moderate stages. METHODS: The Unified Parkinson's Disease Rating Scale and Parkinson's Disease Questionnaire-39 were used to evaluate clinical/functional data and the quality of life. RESULTS: The markers of clinical/functional worsening were drooling (p < 0.004), need for assistance with hygiene (p = 0.02), greater freezing frequency (p = 0.042), bradykinesia (p = 0.031), greater intensity of the resting tremor (p = 0.035) and "pill rolling" (p = 0.001). The decline in quality of life was related to stigma (p = 0.043), greater impairment in cognition (p = 0.002), mobility (p = 0.013) and for daily living activities (p = 0.05), and was considered more significant in men, married, older individuals, and those with a longer time of disease. CONCLUSIONS: The quality of life worsening markers at the moderate stage were related to stigma, worsening of cognition, and to greater impairment in mobility and daily living activities.
Authors: Nayron Medeiros Soares; Gabriela Magalhães Pereira; Vivian Altmann; Rosa Maria Martins de Almeida; Carlos R M Rieder Journal: J Neural Transm (Vienna) Date: 2018-10-29 Impact factor: 3.575
Authors: Sam Chun Sum Yuen; Ka Kit Chua; Linda L D Zhong; Kam Wa Chan; Conrad Kwan Ho Chan; Kam Leung Chan; Zhixiu Lin; Vincent Mok; Alexander Y Lau; Min Li Journal: Chin Med Date: 2022-01-24 Impact factor: 5.455