Literature DB >> 2881049

Evaluation of a clinical case-definition of acquired immunodeficiency syndrome in Africa.

R Colebunders, J M Mann, H Francis, K Bila, L Izaley, N Kakonde, K Kabasele, L Ifoto, N Nzilambi, T C Quinn.   

Abstract

A provisional clinical case-definition for acquired immunodeficiency syndrome (AIDS) developed by the World Health Organisation (WHO) for use in Africa was tested on 174 inpatients at Mama Yemo Hospital, Kinshasa, Zaire. In this hospital population with a 34% infection rate of human immunodeficiency virus (HIV), the clinical case-definition had a specificity of 90%, a sensitivity of 59%, and a predictive value of 74% for HIV seropositivity. These results support the use of the WHO clinical definition for AIDS in Africa. However, since HIV prevalence and disease expression vary, similar evaluations should be carried out in different regions.

Entities:  

Keywords:  Acquired Immunodeficiency Syndrome; Africa; Classification; Developing Countries; Diseases; Examinations And Diagnoses; Hiv Infections; International Agencies; Organizations; Physical Examinations And Diagnoses; Research Methodology; Signs And Symptoms; Un; Viral Diseases; Who

Mesh:

Substances:

Year:  1987        PMID: 2881049     DOI: 10.1016/s0140-6736(87)92099-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  16 in total

1.  For debate. AIDS surveillance in Africa: a reappraisal of case definitions.

Authors:  K M De Cock; R M Selik; B Soro; H Gayle; R L Colebunders
Journal:  BMJ       Date:  1991-11-09

2.  What use is a clinical case definition for AIDS in Africa?

Authors:  C F Gilks
Journal:  BMJ       Date:  1991-11-09

3.  Epidemiology and clinical manifestation of HIV infection in northern Zaire.

Authors:  W Strecker; L Gürtler; M Schilling; M Binibangili; K Strecker
Journal:  Eur J Epidemiol       Date:  1994-02       Impact factor: 8.082

4.  The chemical bases of the various AIDS epidemics: recreational drugs, anti-viral chemotherapy and malnutrition.

Authors:  Peter Duesberg; Claus Koehnlein; David Rasnick
Journal:  J Biosci       Date:  2003-06       Impact factor: 1.826

5.  Risk of tuberculosis in patients with HIV-I and HIV-II infections in Abidjan, Ivory Coast.

Authors:  K M De Cock; E Gnaore; G Adjorlolo; M M Braun; M F Lafontaine; G Yesso; G Bretton; I M Coulibaly; G M Gershy-Damet; R Bretton
Journal:  BMJ       Date:  1991-03-02

6.  Reliability and validity of two HIV/AIDS-specific quality of life instruments adapted for use in HIV-positive Zimbabweans.

Authors:  Tonya N Taylor; Curtis Dolezal; Susan Tross; William C Holmes
Journal:  AIDS Care       Date:  2009-05

7.  Comparison of six serological assays for human immunodeficiency virus antibody detection in developing countries.

Authors:  P Van de Perre; D Nzaramba; S Allen; C H Riggin; S Sprecher-Goldberger; J P Butzler
Journal:  J Clin Microbiol       Date:  1988-03       Impact factor: 5.948

8.  AIDS--A global perspective. Global epidemiology.

Authors:  C F Von Reyn; J M Mann
Journal:  West J Med       Date:  1987-12

9.  Clinical manifestations and the natural history of HIV infection in adults.

Authors:  P Piot; R Colebunders
Journal:  West J Med       Date:  1987-12

Review 10.  Human immunodeficiency virus and acquired immunodeficiency syndrome: correlation but not causation.

Authors:  P H Duesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

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