| Literature DB >> 2881042 |
D J Evans, S J Cashman, M Walport.
Abstract
In a case of progressive systemic sclerosis (PSS), widespread deposition of IgM was found in the media and internal elastic lamina of small muscular arteries. IgA and C3 were also found in some vessels. Antibody eluted from the kidney bound to smooth muscle and elastica of small arteries. These findings suggest that PSS is a vasculopathy which is mediated by complement-fixing antibodies.Entities:
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Year: 1987 PMID： 2881042 DOI： 10.1016/s0140-6736(87)92091-5
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321