| Literature DB >> 28808891 |
Chendie Yao1, Qiong Wu1, Guohua Xu1, Conggang Li2.
Abstract
The emerging of the New Delhi metallo-beta-lactamase (NDM-1) has become one of the greatest threats to the clinical treatment. Although the structure of NDM-1 has been determined by X-ray crystallography, the molecular mechanism and process of catalysis reaction remain elusive. NMR spectroscopy plays a unique role in the characterization of conformational dynamics. Here we report the backbone 1H, 15N and 13C chemical shift assignments of NDM-1 by heteronuclear multidimensional NMR spectroscopy as well as its secondary structure in solution as predicted by TALOS+.Entities:
Keywords: Assignment; NDM-1; NMR; Protein secondary structure
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Year: 2017 PMID： 28808891 DOI： 10.1007/s12104-017-9756-5
Source DB: PubMed Journal: Biomol NMR Assign ISSN： 1874-270X Impact factor: 0.746