Literature DB >> 28808789

Palliative care for children with a yet undiagnosed syndrome.

Jessica I Hoell1, Jens Warfsmann1, Gabriele Gagnon1, Laura Trocan1, Stefan Balzer1, Prasad T Oommen1, Arndt Borkhardt1, Gisela Janßen1, Michaela Kuhlen2.   

Abstract

The number of children without a diagnosis in pediatric palliative home care and the process of decision-making in these children are widely unknown. The study was conducted as single-center retrospective cohort study. Between January 2013 and September 2016, 198 children and young adults were cared for; 27 (13.6%) of these were without a clear diagnosis at the start of pediatric palliative home care. A definite diagnosis was ultimately achieved in three children. Median age was 7 years (0-25), duration of care 569 days (2-2638), and number of home visits 7.5 (2-46). Most patients are still alive (19; 70.4%). Median number of drugs administered was eight (range 2-19); antiepileptics were given most frequently. Despite the lack of a clear diagnosis (and thus prognosis), 13 (48.1%) parents faced with their critically ill and clinically deteriorating children decided in favor of a DNAR order. Comparing this with 15 brain-injured children, signs, symptoms, and supportive needs were similar in both groups.
CONCLUSION: Children without a clear diagnosis are relatively common in pediatric palliative care and have-like all other patients-the right to receive optimized and symptom-adapted palliative care. Parents are less likely to choose treatment limitation for children who lack a definitive diagnosis. What is Known: • A clear diagnosis is usually considered important for best-practice pediatric palliative care (PPC) including advanced care planning (ACP). • Timely initiation of pediatric palliative care (PPC) is highly recommended in children with life-limiting conditions. What is New: • SWAN (syndrome without a name) children show similar signs and symptoms (mostly neurological) and have similar supportive needs as brain-injured children. • Defining treatment limitations in advance care planning is more difficult for parents of SWAN compared to brain-injured children.

Entities:  

Keywords:  Children; End-of-life care; Palliative care; Undiagnosed syndrome

Mesh:

Year:  2017        PMID: 28808789     DOI: 10.1007/s00431-017-2991-z

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  15 in total

1.  Barriers to palliative care for children: perceptions of pediatric health care providers.

Authors:  Betty Davies; Sally A Sehring; J Colin Partridge; Bruce A Cooper; Anne Hughes; Julie C Philp; Aara Amidi-Nouri; Robin F Kramer
Journal:  Pediatrics       Date:  2008-02       Impact factor: 7.124

Review 2.  Paediatric palliative care: challenges and emerging ideas.

Authors:  Stephen Liben; Danai Papadatou; Joanne Wolfe
Journal:  Lancet       Date:  2008-03-08       Impact factor: 79.321

3.  Pediatric Palliative Care and Hospice Care Commitments, Guidelines, and Recommendations.

Authors: 
Journal:  Pediatrics       Date:  2013-11       Impact factor: 7.124

4.  Effectiveness of a pediatric palliative home care team as experienced by parents and health care professionals.

Authors:  René Vollenbroich; Ayda Duroux; Monika Grasser; Monika Brandstätter; Gian Domenico Borasio; Monika Führer
Journal:  J Palliat Med       Date:  2012-01-04       Impact factor: 2.947

5.  The Paediatric Palliative Screening Scale: Further validity testing.

Authors:  Eva Bergstraesser; Michaela Paul; Kaspar Rufibach; Richard D Hain; Leonhard Held
Journal:  Palliat Med       Date:  2014-06       Impact factor: 4.762

6.  Cancer specialists' palliative care referral practices and perceptions: results of a national survey.

Authors:  C E Johnson; A Girgis; C L Paul; D C Currow
Journal:  Palliat Med       Date:  2008-01       Impact factor: 4.762

7.  Experiences in palliative home care of infants with life-limiting conditions.

Authors:  Michaela Kuhlen; Jessica I Höll; Hemmen Sabir; Arndt Borkhardt; Gisela Janßen
Journal:  Eur J Pediatr       Date:  2015-09-28       Impact factor: 3.183

8.  Specialized pediatric palliative home care: a prospective evaluation.

Authors:  Gesa Groh; Gian Domenico Borasio; Carla Nickolay; Hans-Ulrich Bender; Irene von Lüttichau; Monika Führer
Journal:  J Palliat Med       Date:  2013-10-29       Impact factor: 2.947

9.  Pediatric advance care planning from the perspective of health care professionals: a qualitative interview study.

Authors:  Julia D Lotz; Ralf J Jox; Gian Domenico Borasio; Monika Führer
Journal:  Palliat Med       Date:  2014-11-11       Impact factor: 4.762

10.  Keeping all options open: Parents' approaches to advance care planning.

Authors:  Emma Beecham; Linda Oostendorp; Joanna Crocker; Paula Kelly; Andrew Dinsdale; June Hemsley; Jessica Russell; Louise Jones; Myra Bluebond-Langner
Journal:  Health Expect       Date:  2016-09-26       Impact factor: 3.377

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  6 in total

1.  The timing and circumstances of the implementation of pediatric palliative care in Hungarian pediatric oncology.

Authors:  Judit Nyirő; Szilvia Zörgő; Földesi Enikő; Katalin Hegedűs; Péter Hauser
Journal:  Eur J Pediatr       Date:  2018-05-21       Impact factor: 3.183

Review 2.  Clinical perspectives and therapeutic strategies: pediatric autoinflammatory disease-a multi-faceted approach to fever of unknown origin of childhood.

Authors:  Akihiro Yachie
Journal:  Inflamm Regen       Date:  2022-07-02

3.  Facing the large variety of life-limiting conditions in children.

Authors:  Jessica I Hoell; Hannah Weber; Jens Warfsmann; Laura Trocan; Gabriele Gagnon; Mareike Danneberg; Stefan Balzer; Thomas Keller; Gisela Janßen; Michaela Kuhlen
Journal:  Eur J Pediatr       Date:  2019-10-17       Impact factor: 3.183

4.  Challenges of palliative care in children with inborn metabolic diseases.

Authors:  Jessica I Hoell; Jens Warfsmann; Felix Distelmaier; Arndt Borkhardt; Gisela Janßen; Michaela Kuhlen
Journal:  Orphanet J Rare Dis       Date:  2018-07-09       Impact factor: 4.123

5.  Focuses and trends of the studies on pediatric palliative care:A bibliometric analysis from 2004 to 2018.

Authors:  Miao Zhang; Xiaohan Li
Journal:  Int J Nurs Sci       Date:  2020-11-30

Review 6.  Multidisciplinary Care of Patients with Inherited Metabolic Diseases and Epilepsy: Current Perspectives.

Authors:  Birutė Tumienė; Mireia Del Toro Riera; Jurgita Grikiniene; Rūta Samaitiene-Aleknienė; Rūta Praninskienė; Ahmad Ardeshir Monavari; Jolanta Sykut-Cegielska
Journal:  J Multidiscip Healthc       Date:  2022-03-25
  6 in total

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