Maria Giulia Gatti1, Petra Bechtold2, Laura Campo3, Giovanna Barbieri2, Giulia Quattrini2, Andrea Ranzi4, Sabrina Sucato3, Luca Olgiati3, Elisa Polledri3, Michael Romolo2, Laura Iacuzio5, Giuliano Carrozzi2, Paolo Lauriola4, Carlo A Goldoni2, Silvia Fustinoni3. 1. Epidemiology and Risk Communication Unit, Department of Public Health, Local Health Unit, Strada Martiniana, 21, 41126, Modena, Italy. Electronic address: gi.gatti@ausl.mo.it. 2. Epidemiology and Risk Communication Unit, Department of Public Health, Local Health Unit, Strada Martiniana, 21, 41126, Modena, Italy. 3. Department of Clinical Sciences and Community Health, University of Milan and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via S. Barnaba, 8, 20122, Milan, Italy. 4. Environmental Health Reference Centre, Regional Agency for Prevention, Environment and Energy of Emilia-Romagna, Via Begarelli, 13, 41121, Modena, Italy. 5. Post Graduate School in Hygiene and Preventive Medicine, University of Modena and Reggio Emilia, Via Campi, 287, 41125, Modena, Italy.
Abstract
BACKGROUND AND OBJECTIVES: A cross-sectional biomonitoring study was carried out to investigate exposure to incinerator emission in relation to the body burden of selected biomarkers in the population living around the plant. METHODS: Approximately 500 people, aged 18-69 yrs, living within 4 km from the incinerator were randomly selected form the population register. Exposure was measured through fall-out maps of particulate matter (PM), used as tracer for incinerator emissions. Ten metabolized polycyclic aromatic hydrocarbons (PAHs), from naphthalene to chrysene, 1-hydroxypyrene and twelve metals (Cd, Cr, Cu, Hg, Ni, Pb, Ni, Zn, V, Tl, As, Sn) were measured in spot urine samples. Confounders, such as diet, smoking, traffic, occupation and personal characteristics were assessed by questionnaires and objective measurements, and included into multivariate linear regression models. RESULTS: Metal concentrations in urine were in line with or higher than Italian reference limits, besides Cr and V with more than twofold concentrations. Metal levels did not show clear association to exposure categories. Most abundant PAHs were naphthalene (median 26.2 ng/L) and phenanthrene (7.4 ng/L). All PAHs, but benz[a]anthracene and 1-hydroxypyrene, were found in more than 52% of samples, and included in regression models. Significant associations between urinary PAHs and exposure were found, strong for fluorene, and weaker for naphthalene, fluoranthene and pyrene. Results were confirmed by sensitivity analyses. Correlation with variables reported in literature were observed. CONCLUSIONS: The study indicates that the emissions were very low and highlights that specific urinary PAHs provided useful information about the internal dose arising from incinerator emission.
BACKGROUND AND OBJECTIVES: A cross-sectional biomonitoring study was carried out to investigate exposure to incinerator emission in relation to the body burden of selected biomarkers in the population living around the plant. METHODS: Approximately 500 people, aged 18-69 yrs, living within 4 km from the incinerator were randomly selected form the population register. Exposure was measured through fall-out maps of particulate matter (PM), used as tracer for incinerator emissions. Ten metabolized polycyclic aromatic hydrocarbons (PAHs), from naphthalene to chrysene, 1-hydroxypyrene and twelve metals (Cd, Cr, Cu, Hg, Ni, Pb, Ni, Zn, V, Tl, As, Sn) were measured in spot urine samples. Confounders, such as diet, smoking, traffic, occupation and personal characteristics were assessed by questionnaires and objective measurements, and included into multivariate linear regression models. RESULTS:Metal concentrations in urine were in line with or higher than Italian reference limits, besides Cr and V with more than twofold concentrations. Metal levels did not show clear association to exposure categories. Most abundant PAHs were naphthalene (median 26.2 ng/L) and phenanthrene (7.4 ng/L). All PAHs, but benz[a]anthracene and 1-hydroxypyrene, were found in more than 52% of samples, and included in regression models. Significant associations between urinary PAHs and exposure were found, strong for fluorene, and weaker for naphthalene, fluoranthene and pyrene. Results were confirmed by sensitivity analyses. Correlation with variables reported in literature were observed. CONCLUSIONS: The study indicates that the emissions were very low and highlights that specific urinary PAHs provided useful information about the internal dose arising from incinerator emission.
Authors: Laura Campo; Elisa Polledri; Petra Bechtold; Giulia Gatti; Giulia Quattrini; Luca Olgiati; Michael Romolo; Andrea Ranzi; Paolo Lauriola; Giuliano Carrozzi; Silvia Fustinoni Journal: Int J Environ Res Public Health Date: 2018-06-01 Impact factor: 3.390
Authors: Agostino Di Ciaula; Patrizia Gentilini; Giusy Diella; Marco Lopuzzo; Ruggero Ridolfi Journal: Int J Environ Res Public Health Date: 2020-03-16 Impact factor: 3.390