Literature DB >> 28806615

Graphene- gold based nanocomposites applications in cancer diseases; Efficient detection and therapeutic tools.

Lina A Al-Ani1, Mohammed A AlSaadi2, Farkaad A Kadir3, Najihah M Hashim4, Nurhidayatullaili M Julkapli5, Wageeh A Yehye6.   

Abstract

Early detection and efficient treatment of cancer disease remains a drastic challenge in 21st century. Throughout the bulk of funds, studies, and current therapeutics, cancer seems to aggressively advance with drug resistance strains and recurrence rates. Nevertheless, nanotechnologies have indeed given hope to be the next generation for oncology applications. According to US National cancer institute, it is anticipated to revolutionize the perspectives of cancer diagnosis and therapy. With such success, nano-hybrid strategy creates a marvelous preference. Herein, graphene-gold based composites are being increasingly studied in the field of oncology, for their outstanding performance as robust vehicle of therapeutic agents, built-in optical diagnostic features, and functionality as theranostic system. Additional modes of treatments are also applicable including photothermal, photodynamic, as well as combined therapy. This review aims to demonstrate the various cancer-related applications of graphene-gold based hybrids in terms of detection and therapy, highlighting the major attributes that led to designate such system as a promising ally in the war against cancer.
Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Cancer; Detection; Gold nanoparticles; Graphene; Nanocomposite; Therapy

Mesh:

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Year:  2017        PMID: 28806615     DOI: 10.1016/j.ejmech.2017.07.036

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  3 in total

1.  Graphene oxide and its nanocomposites with EDTA or chitosan induce apoptosis in MCF-7 human breast cancer.

Authors:  Ahmed S Doghish; Gharieb S El-Sayyad; Al-Aliaa M Sallam; Waleed F Khalil; Waleed M A El Rouby
Journal:  RSC Adv       Date:  2021-08-31       Impact factor: 4.036

Review 2.  Optical Diagnostic Based on Functionalized Gold Nanoparticles.

Authors:  Jiemei Ou; Zidan Zhou; Zhong Chen; Huijun Tan
Journal:  Int J Mol Sci       Date:  2019-09-05       Impact factor: 5.923

3.  Label-Free and Highly-Sensitive Detection of Ochratoxin A Using One-Pot Synthesized Reduced Graphene Oxide/Gold Nanoparticles-Based Impedimetric Aptasensor.

Authors:  Yasmin Alhamoud; Yingying Li; Haibo Zhou; Ragwa Al-Wazer; Yiying Gong; Shuai Zhi; Danting Yang
Journal:  Biosensors (Basel)       Date:  2021-03-19
  3 in total

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