Tsutomu Tamada1, Justin M Ream, Ankur M Doshi, Samir S Taneja, Andrew B Rosenkrantz. 1. From the *Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, New York University, New York, NY; †Department of Radiology, Kawasaki Medical School, Kurashiki, Japan; and ‡Department of Urologic Oncology, NYU School of Medicine, NYU Langone Medical Center, New York University, New York, NY.
Abstract
OBJECTIVE: The purpose of this study was to compare image quality and tumor assessment at prostate magnetic resonance imaging (MRI) between reduced field-of-view diffusion-weighted imaging (rFOV-DWI) and standard DWI (st-DWI). METHODS: A total of 49 patients undergoing prostate MRI and MRI/ultrasound fusion-targeted biopsy were included. Examinations included st-DWI (field of view [FOV], 200 × 200 mm) and rFOV-DWI (FOV, 140 × 64 mm) using a 2-dimensional (2D) spatially-selective radiofrequency pulse and parallel transmission. Two readers performed qualitative assessments; a third reader performed quantitative evaluation. RESULTS: Overall image quality, anatomic distortion, visualization of capsule, and visualization of peripheral/transition zone edge were better for rFOV-DWI for reader 1 (P ≤ 0.002), although not for reader 2 (P ≥ 0.567). For both readers, sensitivity, specificity, and accuracy for tumor with a Gleason Score (GS) of 3 + 4 or higher were not different (P ≥ 0.289). Lesion clarity was higher for st-DWI for reader 2 (P = 0.008), although similar for reader 1 (P = 0.409). Diagnostic confidence was not different for either reader (P ≥ 0.052). Tumor-to-benign apparent diffusion coefficient ratio was not different (P = 0.675). CONCLUSIONS: Potentially improved image quality of rFOV-DWI did not yield improved tumor assessment. Continued optimization is warranted.
OBJECTIVE: The purpose of this study was to compare image quality and tumor assessment at prostate magnetic resonance imaging (MRI) between reduced field-of-view diffusion-weighted imaging (rFOV-DWI) and standard DWI (st-DWI). METHODS: A total of 49 patients undergoing prostate MRI and MRI/ultrasound fusion-targeted biopsy were included. Examinations included st-DWI (field of view [FOV], 200 × 200 mm) and rFOV-DWI (FOV, 140 × 64 mm) using a 2-dimensional (2D) spatially-selective radiofrequency pulse and parallel transmission. Two readers performed qualitative assessments; a third reader performed quantitative evaluation. RESULTS: Overall image quality, anatomic distortion, visualization of capsule, and visualization of peripheral/transition zone edge were better for rFOV-DWI for reader 1 (P ≤ 0.002), although not for reader 2 (P ≥ 0.567). For both readers, sensitivity, specificity, and accuracy for tumor with a Gleason Score (GS) of 3 + 4 or higher were not different (P ≥ 0.289). Lesion clarity was higher for st-DWI for reader 2 (P = 0.008), although similar for reader 1 (P = 0.409). Diagnostic confidence was not different for either reader (P ≥ 0.052). Tumor-to-benign apparent diffusion coefficient ratio was not different (P = 0.675). CONCLUSIONS: Potentially improved image quality of rFOV-DWI did not yield improved tumor assessment. Continued optimization is warranted.
Authors: Pelin Aksit Ciris; Jr-Yuan George Chiou; Daniel I Glazer; Tzu-Cheng Chao; Clare M Tempany-Afdhal; Bruno Madore; Stephan E Maier Journal: Invest Radiol Date: 2019-04 Impact factor: 6.016
Authors: Francesco Giganti; Veeru Kasivisvanathan; Alex Kirkham; Shonit Punwani; Mark Emberton; Caroline M Moore; Clare Allen Journal: Br J Radiol Date: 2021-07-08 Impact factor: 3.039