Ying-Cheng Chiang1, Yun-Yuan Chen2, Shu-Feng Hsieh1, Chun-Ju Chiang3, San-Lin You4, Wen-Fang Cheng5, Mei-Shu Lai6, Chi-An Chen1. 1. Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan. 2. Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan; Department of Research, Taiwan Blood Services Foundation, Taipei, Taiwan. 3. Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan; Taiwan Cancer Registry, Taipei, Taiwan. 4. Department of Public Health, College of Medicine, Big Data Research Centre, Fu-Jen Catholic University, New Taipei City, Taiwan. Electronic address: yousanlin@gamil.com. 5. Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address: wenfangcheng@yahoo.com. 6. Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Abstract
OBJECTIVE: To evaluate the influence of age, screening interval, and histologic type on the effect of Pap smears in cervical cancer screening. MATERIALS AND METHODS: Data were retrieved from the Taiwan National Cancer Registry and Cervical Cancer Screening Registration System for the period from 2002 to 2010. Age, Pap smear interval, FIGO stage, and histology were further analyzed. RESULTS: A total of 12,294 women with cervical cancer were enrolled, including 10,040 with squamous cell carcinoma (SCC), 1720 with adenocarcinoma (ADC), 401 with adenosquamous carcinoma (ASC), and 133 with small cell neuroendocrine carcinoma (SMC). Women who had a Pap smear at an interval of <3 years had a significantly higher proportion of stage I disease than women who had never undergone cervical cancer screening (p < 0.0001). Greater than 40% of women with SCCs in each age group had never had a Pap smear; however, women with ADCs were predominantly in the younger age and greater than 40% of women with ADCs had Pap smear at intervals < 3 years. CONCLUSIONS: Pap smear is more effective in screening for cervical SCCs compared to cervical ADCs. Improving adherence to screening recommendations is important for the prevention of cervical SCC, especially in elderly women.
OBJECTIVE: To evaluate the influence of age, screening interval, and histologic type on the effect of Pap smears in cervical cancer screening. MATERIALS AND METHODS: Data were retrieved from the Taiwan National Cancer Registry and Cervical Cancer Screening Registration System for the period from 2002 to 2010. Age, Pap smear interval, FIGO stage, and histology were further analyzed. RESULTS: A total of 12,294 women with cervical cancer were enrolled, including 10,040 with squamous cell carcinoma (SCC), 1720 with adenocarcinoma (ADC), 401 with adenosquamous carcinoma (ASC), and 133 with small cell neuroendocrine carcinoma (SMC). Women who had a Pap smear at an interval of <3 years had a significantly higher proportion of stage I disease than women who had never undergone cervical cancer screening (p < 0.0001). Greater than 40% of women with SCCs in each age group had never had a Pap smear; however, women with ADCs were predominantly in the younger age and greater than 40% of women with ADCs had Pap smear at intervals < 3 years. CONCLUSIONS:Pap smear is more effective in screening for cervical SCCs compared to cervical ADCs. Improving adherence to screening recommendations is important for the prevention of cervical SCC, especially in elderly women.
Authors: Rancés Blanco; Diego Carrillo-Beltrán; Juan P Muñoz; Julio C Osorio; Julio C Tapia; Verónica A Burzio; Iván Gallegos; Gloria M Calaf; Paola Chabay; Francisco Aguayo Journal: Microorganisms Date: 2022-04-24
Authors: Chia-Hao Liu; Yu-Chieh Lee; Jeff Chien-Fu Lin; I-San Chan; Na-Rong Lee; Wen-Hsun Chang; Wei-Min Liu; Peng-Hui Wang Journal: Int J Environ Res Public Health Date: 2019-10-11 Impact factor: 3.390
Authors: Emmanuel N S Sackey; Manideepthi Pemmaraju; Marie R Griffin; Jessica L Castilho Journal: BMC Womens Health Date: 2022-03-12 Impact factor: 2.809