Literature DB >> 28805587

Osteoporosis: A Hidden Nonmotor Face of Parkinson's Disease.

Vinod Metta1, Tamara C Sanchez2, Chandrasekhara Padmakumar3.   

Abstract

Osteoporosis is a "hidden nonmotor face" of Parkinson's disease and a cause of considerable morbidity in the older general population and in Parkinson's disease patients. Some regard this as a "hidden epidemic." Women are overrepresented and have considerable problems related to osteoporosis. In general osteoporosis leads to reduced mobility aggravating the motor syndrome of PD. The nonmotor aspects and impact of osteoporosis in PD have remained unexplored. Possible nonmotor consequences include a range of pain syndromes related to local pain, fractures, falls, and injuries as well as pathological fractures and radiculopathy. In addition depression, sleep dysfunction, dementia, as well as fear of falling also complicate the clinical picture. Quality of life deteriorates both for the patient and career. Pathways of care do not always include assessments for osteoporosis and needs to become obligatory particularly in older female PD patients. Active management strategies then need to be undertaken for osteoporosis in PD. Related motor and nonmotor consequences also highlight the importance of multidisciplinary treatment in PD particularly when dealing with osteoporosis.
© 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Bone mineral density; Nonmotor symptoms; Osteopenia; Osteoporosis; Parkinson's disease

Mesh:

Year:  2017        PMID: 28805587     DOI: 10.1016/bs.irn.2017.05.034

Source DB:  PubMed          Journal:  Int Rev Neurobiol        ISSN: 0074-7742            Impact factor:   3.230


  13 in total

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2.  Chlorpyrifos Exposure Induces Parkinsonian Symptoms and Associated Bone Loss in Adult Swiss Albino Mice.

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6.  A genome-wide scan for pleiotropy between bone mineral density and nonbone phenotypes.

Authors:  Maria A Christou; Georgios Ntritsos; Georgios Markozannes; Fotis Koskeridis; Spyros N Nikas; David Karasik; Douglas P Kiel; Evangelos Evangelou; Evangelia E Ntzani
Journal:  Bone Res       Date:  2020-07-01       Impact factor: 13.567

7.  Bone Mineral Density, TBS, and Body Composition Indexes in Ukrainian Men with Parkinson's Disease.

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Review 8.  Management of Pain in Parkinson's Disease.

Authors:  Carsten Buhmann; Jan Kassubek; Wolfgang H Jost
Journal:  J Parkinsons Dis       Date:  2020       Impact factor: 5.568

Review 9.  The relationships of vitamin D, vitamin D receptor gene polymorphisms, and vitamin D supplementation with Parkinson's disease.

Authors:  Lingling Lv; Xuling Tan; Xinke Peng; Rongrong Bai; Qile Xiao; Ting Zou; Jieqiong Tan; Hainan Zhang; Chunyu Wang
Journal:  Transl Neurodegener       Date:  2020-09-01       Impact factor: 8.014

Review 10.  Current Perspectives on Aerobic Exercise in People with Parkinson's Disease.

Authors:  Sabine Schootemeijer; Nicolien M van der Kolk; Bastiaan R Bloem; Nienke M de Vries
Journal:  Neurotherapeutics       Date:  2020-10       Impact factor: 7.620

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