OBJECTIVES: This work focused on extracting novel and validated digital high-throughput features to present a detailed and comprehensive description of the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) with the goal of improving the accuracy of ultrasound breast cancer diagnosis. METHODS: First, the phase congruency approach was used to segment the tumors automatically. Second, high-throughput features were designed and extracted on the basis of each BI-RADS category. Then features were selected based on the basis of a Student t test and genetic algorithm. Finally, the AdaBoost classifier was used to differentiate benign tumors from malignant ones. RESULTS: Experiments were conducted on a database of 138 pathologically proven breast tumors. The system was compared with 6 state-of-art BI-RADS feature extraction methods. By using leave-one-out cross-validation, our system achieved a highest overall accuracy of 93.48%, a sensitivity of 94.20%, a specificity of 92.75%, and an area under the receiver operating characteristic curve of 95.67%, respectively, which were superior to those of other methods. CONCLUSIONS: The experiments demonstrated that our computerized BI-RADS feature system was capable of helping radiologists detect breast cancers more accurately and provided more guidance for final decisions.
OBJECTIVES: This work focused on extracting novel and validated digital high-throughput features to present a detailed and comprehensive description of the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) with the goal of improving the accuracy of ultrasound breast cancer diagnosis. METHODS: First, the phase congruency approach was used to segment the tumors automatically. Second, high-throughput features were designed and extracted on the basis of each BI-RADS category. Then features were selected based on the basis of a Student t test and genetic algorithm. Finally, the AdaBoost classifier was used to differentiate benign tumors from malignant ones. RESULTS: Experiments were conducted on a database of 138 pathologically proven breast tumors. The system was compared with 6 state-of-art BI-RADS feature extraction methods. By using leave-one-out cross-validation, our system achieved a highest overall accuracy of 93.48%, a sensitivity of 94.20%, a specificity of 92.75%, and an area under the receiver operating characteristic curve of 95.67%, respectively, which were superior to those of other methods. CONCLUSIONS: The experiments demonstrated that our computerized BI-RADS feature system was capable of helping radiologists detect breast cancers more accurately and provided more guidance for final decisions.