Literature DB >> 28804829

Lupus Anticoagulant Testing: Activated Partial Thromboplastin Time (APTT) and Silica Clotting Time (SCT).

Armando Tripodi1, Veena Chantarangkul2.   

Abstract

Actvated partial thromboplastin time and its congener test Silica clotting time are used for the laboratory detection of lupus anticoagulants. Their performance consists of mixing test plasma with activators of the contact coagulation factors, phospholipids and calcium chloride, and recording the clotting time. Here we describe the principle, performance and extensive practical details of the two methods, the problems that may be encountered and how they can be identified and overcome.

Entities:  

Keywords:  Activated partial thromboplastin time; Antiphosphoilpid syndrome; Laboratory test; Silica clotting time; Thrombosis

Mesh:

Substances:

Year:  2017        PMID: 28804829     DOI: 10.1007/978-1-4939-7196-1_15

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  4 in total

Review 1.  Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants.

Authors:  Emmanuel J Favaloro; Leonardo Pasalic
Journal:  Res Pract Thromb Haemost       Date:  2022-03-15

2.  A multi-laboratory assessment of lupus anticoagulant assays performed on the ACL TOP 50 family for harmonized testing in a large laboratory network.

Authors:  Emmanuel J Favaloro; Soma Mohammed; Ronny Vong; Kent Chapman; Priscilla Swanepoel; Geoffrey Kershaw; Nancy Cai; Sarah Just; Lynne Connelly; Timothy Brighton; Leonardo Pasalic
Journal:  Int J Lab Hematol       Date:  2022-03-01       Impact factor: 3.450

3.  Differentiating central nervous system demyelinating disorders: The role of clinical, laboratory, imaging characteristics and peripheral blood type I interferon activity.

Authors:  Dimitris K Karathanasis; Anna Rapti; Adrianos Nezos; Charalampos Skarlis; Constantinos Kilidireas; Clio P Mavragani; Maria Eleftheria Evangelopoulos
Journal:  Front Pharmacol       Date:  2022-08-12       Impact factor: 5.988

4.  Differential diagnosis and clinical management of isolated prolonged activated partial thromboplastin time in a patient with Hashimoto thyroiditis-associated thyroid cancer: A case report.

Authors:  Yuhong Zhong; Biyong Yan; Zhongqi Yu; Lin Wang
Journal:  Medicine (Baltimore)       Date:  2021-07-09       Impact factor: 1.817

  4 in total

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