| Literature DB >> 28803510 |
Natalia Golender1,2, Yevgeny Khinich1,2, Anna Gorohov1,2, Itzik Abramovitz1,2, Velizar Bumbarov1,2.
Abstract
In September 2015, a large outbreak caused by epizootic hemorrhagic disease virus (EHDV) was identified in Israeli dairy and beef farms. The main clinical signs were reduced milk production, weakness, drooling, lameness and recumbency, fever, slight erythema of nasal and oral mucosae, weight loss, and abortion. Dyspnea, cachexia, and death were observed less frequently. The clinical diagnosis was confirmed by ELISAs and EHDV-specific real-time reverse transcription PCR (RT-rtPCR), followed by conventional RT-PCR of the VP2 gene and sequence analysis. According to the sequence and phylogenetic analysis of theVP2 gene, the 2015 Israeli EHD outbreak was caused by EHDV-6, which was found not only in clinically ill cattle, but also in aborted fetuses.Entities:
Keywords: Abortion; Orbivirus; Reoviridae; cattle; epizootic hemorrhagic disease; phylogeny; sequence analysis
Mesh:
Year: 2017 PMID: 28803510 DOI: 10.1177/1040638717726826
Source DB: PubMed Journal: J Vet Diagn Invest ISSN: 1040-6387 Impact factor: 1.279