Literature DB >> 2880341

Comparison of the effects of atenolol, sotalol and labetalol on muscle blood flow in man.

G V Raman, F M Mwongera, D J Warren.   

Abstract

A double-blind study of the effect of three beta-adrenoceptor blocking drugs (beta-blockers) on exercise muscle blood flow (MBF) in 14 normotensive volunteers was carried out. MBF was measured by the xenon-133 clearance technique. MBF was not altered by placebo, sotalol or labetalol. Atenolol significantly reduced MBF compared with placebo, sotalol and labetalol. We conclude that sotalol and labetalol may be more useful than conventional beta-blockers for treatment of hypertension or angina in association with peripheral vascular disease.

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Year:  1986        PMID: 2880341      PMCID: PMC2422788          DOI: 10.1136/pgmj.62.731.841

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  14 in total

1.  BIRDS AND INSECTICIDES.

Authors:  H C MAGUIRE
Journal:  Lancet       Date:  1964-04-18       Impact factor: 79.321

2.  Effect of sotalol on haemodynamics and renin-angiotensin-aldosterone system in hypertensive patients.

Authors:  A Verniory; M Staroukine; F Delwiche; M Telerman
Journal:  Clin Sci Mol Med       Date:  1976-07

3.  Raynaud's phenomenon as side effect of beta-blockers in hypertension.

Authors:  A J Marshall; C J Roberts; D W Barritt
Journal:  Br Med J       Date:  1976-06-19

4.  Peripheral skin necrosis complicating beta-blockade.

Authors:  P J Rees
Journal:  Br Med J       Date:  1979-04-07

5.  Sotalol-induced beta blockade in cardiac patients.

Authors:  H Brooks; J Banas; S Meister; M Szucs; J Dalen; L Dexter
Journal:  Circulation       Date:  1970-07       Impact factor: 29.690

6.  Muscle blood flow during exercise in normal man studied by the 133Xenon clearance method.

Authors:  J P Clausen; N A Lassen
Journal:  Cardiovasc Res       Date:  1971-04       Impact factor: 10.787

7.  Peripheral gangrene complicating beta-blockade.

Authors:  J A Vale; S J Van de Pette; T M Price
Journal:  Lancet       Date:  1977-08-20       Impact factor: 79.321

8.  Assessment of cadmium telluride detector system for measurement of muscle blood flow during dynamic exercise in man.

Authors:  R S Smith; J Bojsen; D J Warren
Journal:  Cardiovasc Res       Date:  1981-12       Impact factor: 10.787

9.  Sotalol-induced delayed ventricular repolarization in man.

Authors:  N Edvardsson; I Hirsch; H Emanuelsson; J Pontén; S B Olsson
Journal:  Eur Heart J       Date:  1980-10       Impact factor: 29.983

10.  Effects of propranolol and metoprolol on the peripheral circulation.

Authors:  P D McSorley; D J Warren
Journal:  Br Med J       Date:  1978-12-09
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  1 in total

Review 1.  Sotalol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use.

Authors:  B N Singh; P Deedwania; K Nademanee; A Ward; E M Sorkin
Journal:  Drugs       Date:  1987-09       Impact factor: 9.546

  1 in total

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