Literature DB >> 28802874

Targeting gastrointestinal nutrient sensing mechanisms to treat obesity.

Mariana Norton1, Kevin G Murphy2.   

Abstract

Gut hormones have important roles in the regulation of appetite and glucose homeostasis. Understanding how macronutrient sensing in the gastrointestinal tract modulates gut hormone release may reveal novel pharmacological or dietary approaches to metabolic disease. In this short review we discuss the mechanisms by which the gut senses macronutrients and the products of macronutrient digestion, and their putative utility in treating obesity and related conditions.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID： 28802874     DOI： 10.1016/j.coph.2017.07.005

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN： 1471-4892            Impact factor:   5.547


  6 in total

Review 1.  Macronutrient Sensing in the Oral Cavity and Gastrointestinal Tract: Alimentary Tastes.

Authors:  Russell Keast; Andrew Costanzo; Isabella Hartley
Journal:  Nutrients       Date:  2021-02-19       Impact factor: 5.717

Review 2.  A Review on the Role of Food-Derived Bioactive Molecules and the Microbiota-Gut-Brain Axis in Satiety Regulation.

Authors:  Nuria A Pizarroso; Pablo Fuciños; Catarina Gonçalves; Lorenzo Pastrana; Isabel R Amado
Journal:  Nutrients       Date:  2021-02-16       Impact factor: 5.717

3.  Anti-Obesity Effect of Theabrownin from Dark Tea in C57BL/6J Mice Fed a High-Fat Diet by Metabolic Profiles through Gut Microbiota Using Untargeted Metabolomics.

Authors:  Hang-Yu Li; Si-Yu Huang; Ruo-Gu Xiong; Si-Xia Wu; Dan-Dan Zhou; Adila Saimaiti; Min Luo; Hui-Lian Zhu; Hua-Bin Li
Journal:  Foods       Date:  2022-09-27

Review 4.  Impact of Protein Intake in Older Adults with Sarcopenia and Obesity: A Gut Microbiota Perspective.

Authors:  Konstantinos Prokopidis; Mavil May Cervo; Anoohya Gandham; David Scott
Journal:  Nutrients       Date:  2020-07-30       Impact factor: 5.717

5.  L-Arginine Increases Postprandial Circulating GLP-1 and PYY Levels in Humans.

Authors:  Anjali Amin; Christina Neophytou; Shermaine Thein; Niamh M Martin; Amin Alamshah; Eleanor Spreckley; Stephen R Bloom; Kevin G Murphy
Journal:  Obesity (Silver Spring)       Date:  2018-11       Impact factor: 5.002

Review 6.  Protein- and Calcium-Mediated GLP-1 Secretion: A Narrative Review.

Authors:  Jonathan D Watkins; Françoise Koumanov; Javier T Gonzalez
Journal:  Adv Nutr       Date:  2021-12-01       Impact factor: 8.701
  6 in total

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