Literature DB >> 2880272

Pharmacological studies of somatostatin and somatostatin-analogues: therapeutic advances and perspectives.

J P Moreau, F V DeFeudis.   

Abstract

This article is aimed at reviewing and analyzing studies that are related to the possible therapeutic use of a potent and ubiquitously-distributed hormone--somato-statin (SS-14), and its analogues. Administration of these substances has provided beneficial effects in treating acromegaly, gastro-intestinal hemorrhagic and hypersecretory disorders, acute pancreatitis, diabetes mellitus, and certain types of cancer. Further studies with SS-14-analogues might provide new therapies for treating certain life-threatening disorders of man.

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Year:  1987        PMID： 2880272     DOI： 10.1016/0024-3205(87)90107-x

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  8 in total

1.  Somatostatin-like immunoreactivity in non-pyramidal neurons of the human entorhinal region.

Authors:  B Friederich-Ecsy; E Braak; H Braak; A Probst
Journal:  Cell Tissue Res       Date:  1988-11       Impact factor: 5.249

2.  Pharmacokinetic study and effects on growth hormone secretion in healthy volunteers of the new somatostatin analogue BIM 23014.

Authors:  J M Kuhn; C Basin; M Mollard; B de Rougé; C Baudoin; R Obach; G Tolis
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

3.  SMS 201-995-induced stimulation of gastric acid secretion via the dorsal vagal complex and inhibition via the hypothalamus in anaesthetized rats.

Authors:  M Yoneda; Y Taché
Journal:  Br J Pharmacol       Date:  1995-10       Impact factor: 8.739

4.  Coincidence of EGF receptors and somatostatin receptors in meningiomas but inverse, differentiation-dependent relationship in glial tumors.

Authors:  J C Reubi; U Horisberger; W Lang; J W Koper; R Braakman; S W Lamberts
Journal:  Am J Pathol       Date:  1989-02       Impact factor: 4.307

Review 5.  Hormonal therapy of pancreatic carcinoma. Rationale and perspectives.

Authors:  D Perilli; C Mansi; V Savarino; G Celle
Journal:  Int J Pancreatol       Date:  1993-06

6.  Effects of long-acting somatostatin analog (SMS 201-995) on eicosanoid synthesis and survival in rats with acute necrotizing pancreatitis.

Authors:  B van Ooijen; C J Tinga; W J Kort; F J Zijlstra; S W Lamberts; J H Wilson
Journal:  Dig Dis Sci       Date:  1992-09       Impact factor: 3.199

7.  Culture of fetal alveolar epithelial type II cells in serum-free medium.

Authors:  C Fraslon; G Rolland; J R Bourbon; M Rieutort; C Valenza
Journal:  In Vitro Cell Dev Biol       Date:  1991-11

8.  Experimental and clinical studies with somatostatin analogue octreotide in small cell lung cancer.

Authors:  V M Macaulay; I E Smith; M J Everard; J D Teale; J C Reubi; J L Millar
Journal:  Br J Cancer       Date:  1991-09       Impact factor: 7.640
  8 in total

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