Literature DB >> 28802541

Opioid doses and acute care utilization outcomes for adults with sickle cell disease: ED versus acute care unit.

Robert E Molokie1, Chariz Montminy2, Corissa Dionisio3, Muhammad Ahmen Farooqui4, Michel Gowhari5, Yingwei Yao6, Marie L Suarez7, Miriam O Ezenwa8, Judith M Schlaeger9, Zaijie J Wang10, Diana J Wilkie11.   

Abstract

BACKGROUND: Acute care units (ACUs) with focused sickle cell disease (SCD) care have been shown to effectively address pain and limit hospitalizations compared to emergency departments (ED), the reason for differences in admission rates is understudied. Our aim was compare effects of usual care for adult SCD pain in ACU and ED on opioid doses and discharge pain ratings, hospital admission rates and lengths of stay.
METHODS: In a retrospective, comparative cohort, single academic tertiary center study, 148 adults with sickle cell pain received care in the ED, ACU or both. From the medical records we documented opioid doses, unit discharge pain ratings, hospital admission rates, and lengths of stay.
FINDINGS: Pain on admission to the ED averaged 8.7±1.5 and to the ACU averaged 8.0±1.6. The average pain on discharge from the ED was 6.4±3.0 and for the ACU was 4.5±2.5. 70% of the 144 ED visits resulted in hospital admissions as compared to 37% of the 73 ACU visits. Admissions from the ED or ACU had similar inpatient lengths of stay. Significant differences between ED and ACU in first opioid dose and hourly opioid dose were noted.
CONCLUSIONS: Applying guidelines for higher dosing of opioids for acute painful episodes in adults with SCD in ACU was associated with improved pain outcomes and decreased hospitalizations, compared to ED. Adoption of this approach for SCD pain in ED may result in improved outcomes, including a decrease in hospital admissions. Published by Elsevier Inc.

Entities:  

Keywords:  Acute care unit; Emergency department; Hospital admission; Opioid; Pain; Sickle cell disease

Mesh:

Substances:

Year:  2017        PMID: 28802541      PMCID: PMC7083150          DOI: 10.1016/j.ajem.2017.07.037

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  17 in total

Review 1.  Treating sickle cell pain: an update from the Georgia comprehensive sickle cell center.

Authors:  Allan Platt; James R Eckman; JoAnn Beasley; Gaynell Miller
Journal:  J Emerg Nurs       Date:  2002-08       Impact factor: 1.836

2.  Day case management of sickle pain: 3 years experience in a UK sickle cell unit.

Authors:  J Wright; D Bareford; C Wright; G Augustine; K Olley; L Musamadi; C Dhanda; C Knight
Journal:  Br J Haematol       Date:  2004-09       Impact factor: 6.998

3.  Emergency department visits made by patients with sickle cell disease: a descriptive study, 1999-2007.

Authors:  Hussain R Yusuf; Hani K Atrash; Scott D Grosse; Christopher S Parker; Althea M Grant
Journal:  Am J Prev Med       Date:  2010-04       Impact factor: 5.043

4.  Safety and Utility of Quantitative Sensory Testing among Adults with Sickle Cell Disease: Indicators of Neuropathic Pain?

Authors:  Miriam O Ezenwa; Robert E Molokie; Zaijie Jim Wang; Yingwei Yao; Marie L Suarez; Cherese Pullum; Judith M Schlaeger; Roger B Fillingim; Diana J Wilkie
Journal:  Pain Pract       Date:  2015-01-12       Impact factor: 3.183

5.  The burden of emergency department use for sickle-cell disease: an analysis of the national emergency department sample database.

Authors:  Sophie Lanzkron; C Patrick Carroll; Carlton Haywood
Journal:  Am J Hematol       Date:  2010-10       Impact factor: 10.047

6.  Patient-reported outcomes: descriptors of nociceptive and neuropathic pain and barriers to effective pain management in adult outpatients with sickle cell disease.

Authors:  Diana J Wilkie; Robert Molokie; Debra Boyd-Seal; Marie L Suarez; Young Ok Kim; Shiping Zong; Harriet Wittert; Zhongsheng Zhao; Yogen Saunthararajah; Zaijie J Wang
Journal:  J Natl Med Assoc       Date:  2010-01       Impact factor: 1.798

7.  Medical care utilization and mortality in sickle cell disease: a population-based study.

Authors:  Sadhna M Shankar; Patrick G Arbogast; Ed Mitchel; William O Cooper; Winfred C Wang; Marie R Griffin
Journal:  Am J Hematol       Date:  2005-12       Impact factor: 10.047

8.  Day-care management of sickle cell painful crisis in Jamaica: a model applicable elsewhere?

Authors:  M A Ware; I Hambleton; I Ochaya; G R Serjeant
Journal:  Br J Haematol       Date:  1999-01       Impact factor: 6.998

9.  Postoperative analgesics for children and adolescents: prescription and administration.

Authors:  M D Tesler; D J Wilkie; W L Holzemer; M C Savedra
Journal:  J Pain Symptom Manage       Date:  1994-02       Impact factor: 3.612

10.  Healthcare utilization and expenditures for low income children with sickle cell disease.

Authors:  Jean L Raphael; Craig L Dietrich; Deborah Whitmire; Donald H Mahoney; Brigitta U Mueller; Angelo P Giardino
Journal:  Pediatr Blood Cancer       Date:  2009-02       Impact factor: 3.167

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  12 in total

1.  American Society of Hematology 2020 guidelines for sickle cell disease: management of acute and chronic pain.

Authors:  Amanda M Brandow; C Patrick Carroll; Susan Creary; Ronisha Edwards-Elliott; Jeffrey Glassberg; Robert W Hurley; Abdullah Kutlar; Mohamed Seisa; Jennifer Stinson; John J Strouse; Fouza Yusuf; William Zempsky; Eddy Lang
Journal:  Blood Adv       Date:  2020-06-23

2.  Impact of early analgesia on hospitalization outcomes for sickle cell pain crisis.

Authors:  Jason Payne; Inmaculada Aban; Lee M Hilliard; Jennifer Madison; Christina Bemrich-Stolz; Thomas H Howard; Amanda Brandow; Emily Waite; Jeffrey D Lebensburger
Journal:  Pediatr Blood Cancer       Date:  2018-08-27       Impact factor: 3.167

3.  Randomized clinical trial of computerized PAINRelieveIt® for patients with sickle cell disease: PAINReportIt® and PAINUCope®.

Authors:  Brenda W Dyal; Miriam O Ezenwa; Yingwei Yao; Robert E Molokie; Zaijie J Wang; Samir K Ballas; Marie L Suarez; Diana J Wilkie
Journal:  Patient Educ Couns       Date:  2019-08-17

4.  Differences in Sensory Pain, Expectation, and Satisfaction Reported by Outpatients with Cancer or Sickle Cell Disease.

Authors:  Miriam O Ezenwa; Robert E Molokie; Zaijie Jim Wang; Yingwei Yao; Marie L Suarez; Brenda Dyal; Khulud Abudawood; Diana J Wilkie
Journal:  Pain Manag Nurs       Date:  2018-03-01       Impact factor: 1.929

5.  Patient-Reported Outcomes and Economic Burden of Adults with Sickle Cell Disease in the United States: A Systematic Review.

Authors:  Soyon Lee; Diana K Vania; Menaka Bhor; Dennis Revicki; Seye Abogunrin; Grammati Sarri
Journal:  Int J Gen Med       Date:  2020-07-07

6.  Glucocorticoid receptor single nucleotide polymorphisms are associated with acute crisis pain in sickle cell disease.

Authors:  Ellie H Jhun; Nilanjana Sadhu; Yingwei Yao; Ying He; Robert E Molokie; Diana J Wilkie; Zaijie Jim Wang
Journal:  Pharmacogenomics       Date:  2018-08-06       Impact factor: 2.533

7.  Opioid Prescription Filling Trends Among Children with Sickle Cell Disease After the Release of State-Issued Guidelines on Pain Management.

Authors:  Susan E Creary; Deena J Chisolm; Sharon K Wrona; Jennifer N Cooper
Journal:  Pain Med       Date:  2020-10-01       Impact factor: 3.750

8.  Acupuncture for chronic pain in adults with sickle cell disease: a mixed-methods pilot study.

Authors:  Hongjin Li; Crystal L Patil; Robert E Molokie; Franklin Njoku; Alana D Steffen; Ardith Z Doorenbos; Judith M Schlaeger
Journal:  Acupunct Med       Date:  2021-06-03       Impact factor: 1.976

9.  Implementation of Individualized Pain Care Plans Decreases Length of Stay and Hospital Admission Rates for High Utilizing Adults with Sickle Cell Disease.

Authors:  Jena L Welch-Coltrane; Anthony A Wachnik; Meredith C B Adams; Cherie R Avants; Howard A Blumstein; Amber K Brooks; Andrew M Farland; Joshua B Johnson; Manoj Pariyadath; Erik C Summers; Robert W Hurley
Journal:  Pain Med       Date:  2021-08-06       Impact factor: 3.750

10.  Vasopressin SNP pain factors and stress in sickle cell disease.

Authors:  Keesha L Powell-Roach; Yingwei Yao; Ellie H Jhun; Ying He; Marie L Suarez; Miriam O Ezenwa; Robert E Molokie; Zaijie Jim Wang; Diana J Wilkie
Journal:  PLoS One       Date:  2019-11-11       Impact factor: 3.240

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