Narumi Kojima1, Miji Kim2, Kyoko Saito3, Yuko Yoshida4, Hirohiko Hirano5, Shuichi Obuchi6, Hiroyuki Shimada7, Takao Suzuki8, Hunkyung Kim9. 1. Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan. Electronic address: nkojima@tmig.or.jp. 2. East-West Medical Research Institute, Kyung Hee University, 23, Kyung Hee Dae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea. Electronic address: mijiak@khu.ac.kr. 3. Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. Electronic address: kyos@yokohama-cu.ac.jp. 4. Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan. Electronic address: yossy@tmig.or.jp. 5. Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan. Electronic address: hhirano@tmig.or.jp. 6. Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan. Electronic address: obuchipc@tmig.or.jp. 7. Research Institute, National Center for Geriatrics and Gerontology, 35 Gengo, Morioka-machi, Obu-shi, Aichi 474-8511, Japan. Electronic address: shimada@ncgg.go.jp. 8. Research Institute, National Center for Geriatrics and Gerontology, 35 Gengo, Morioka-machi, Obu-shi, Aichi 474-8511, Japan. Electronic address: suzutaka@ncgg.go.jp. 9. Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan. Electronic address: kimhk@tmig.or.jp.
Abstract
PURPOSE: This study aimed to determine the predictors of knee osteoarthritis in community-dwelling elderly Japanese women. METHODS: In this prospective cohort study, The Tokyo Metropolitan Institute of Gerontology collected baseline data in 2008 and follow-up data in 2012 for participants from the Itabashi Ward of Tokyo, Japan. Participants were asked at each time point if they had been diagnosed with knee osteoarthritis. The baseline evaluation was conducted with 1289 community-dwelling women aged 75-85 years, of which 992 reported no history of knee osteoarthritis. The follow-up survey targeted these 992 participants; we obtained history of knee osteoarthritis from 867 of these participants. The baseline evaluation also included collection of anthropometric, fitness, hematologic, and lifestyle data. RESULTS: We performed logistic regression analysis of the cross-sectional data at baseline. Participants who reported fewer light exercise sessions (≤2-4days/week) had lower odds ratios for history of self-reported knee osteoarthritis than those who reported more frequent exercise (≥5-6days/week). Logistic regression analysis of the longitudinal data revealed that slow walking speed (<65.22m/min), low serum albumin levels (<4.10g/dL), and low frequency of soy product consumption (≤1 time per 2days) at baseline resulted in higher odds ratios for incidence of self-reported knee osteoarthritis during the 4-year follow-up period. CONCLUSIONS: The results suggest that slow walking speed, low serum albumin, and insufficient consumption of soy products are predictors for knee osteoarthritis in elderly Japanese women. These results could help in the design of knee osteoarthritis prevention programs for elderly women.
PURPOSE: This study aimed to determine the predictors of knee osteoarthritis in community-dwelling elderly Japanese women. METHODS: In this prospective cohort study, The Tokyo Metropolitan Institute of Gerontology collected baseline data in 2008 and follow-up data in 2012 for participants from the Itabashi Ward of Tokyo, Japan. Participants were asked at each time point if they had been diagnosed with knee osteoarthritis. The baseline evaluation was conducted with 1289 community-dwelling women aged 75-85 years, of which 992 reported no history of knee osteoarthritis. The follow-up survey targeted these 992 participants; we obtained history of knee osteoarthritis from 867 of these participants. The baseline evaluation also included collection of anthropometric, fitness, hematologic, and lifestyle data. RESULTS: We performed logistic regression analysis of the cross-sectional data at baseline. Participants who reported fewer light exercise sessions (≤2-4days/week) had lower odds ratios for history of self-reported knee osteoarthritis than those who reported more frequent exercise (≥5-6days/week). Logistic regression analysis of the longitudinal data revealed that slow walking speed (<65.22m/min), low serum albumin levels (<4.10g/dL), and low frequency of soy product consumption (≤1 time per 2days) at baseline resulted in higher odds ratios for incidence of self-reported knee osteoarthritis during the 4-year follow-up period. CONCLUSIONS: The results suggest that slow walking speed, low serum albumin, and insufficient consumption of soy products are predictors for knee osteoarthritis in elderly Japanese women. These results could help in the design of knee osteoarthritis prevention programs for elderly women.