Literature DB >> 2880114

Effect of oestrogen and testosterone implants on psychological disorders in the climacteric.

J C Montgomery, L Appleby, M Brincat, E Versi, A Tapp, P B Fenwick, J W Studd.   

Abstract

In a double-blind trial oestradiol, oestradiol/testosterone, or placebo implants were assessed for their effects on psychological symptoms in women attending a menopause clinic. After two months, women receiving active treatment scored better than the placebo group on a self-rating scale of distress, on anxiety, and on depression (p less than 0.05). Postmenopausal but not perimenopausal women improved after placebo, and at 4 months the scores in the three groups no longer differed significantly.

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Year:  1987        PMID: 2880114     DOI: 10.1016/s0140-6736(87)92026-5

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  26 in total

1.  Neurobiological Underpinnings of the Estrogen - Mood Relationship.

Authors:  Whitney Wharton; Carey E Gleason; Sandra R M S Olson; Cynthia M Carlsson; Sanjay Asthana
Journal:  Curr Psychiatry Rev       Date:  2012-08-01

2.  Complications of hormone replacement therapy in post-menopausal women.

Authors:  J Studd
Journal:  J R Soc Med       Date:  1992-07       Impact factor: 5.344

3.  Double-blind, placebo-controlled, hormonal, syndromal and EEG mapping studies with transdermal oestradiol therapy in menopausal depression.

Authors:  B Saletu; N Brandstätter; M Metka; M Stamenkovic; P Anderer; H V Semlitsch; G Heytmanek; J Huber; J Grünberger; L Linzmayer
Journal:  Psychopharmacology (Berl)       Date:  1995-12       Impact factor: 4.530

4.  Depression and the menopause.

Authors:  J W Studd; N R Watson; J Montgomery
Journal:  BMJ       Date:  1990-06-23

5.  Effect of combined implants of oestradiol and testosterone on libido in postmenopausal women.

Authors:  L Appleby; J Montgomery
Journal:  Br Med J (Clin Res Ed)       Date:  1987-05-30

6.  Symptoms of oestrogen deficiency in women with oestradiol implants.

Authors:  J Studd; A Henderson; T Garnett; N Watson; M Savvas
Journal:  BMJ       Date:  1989-12-02

Review 7.  Role of estrogen in the aetiology and treatment of mood disorders.

Authors:  U Halbreich; L S Kahn
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

Review 8.  Sex hormones and mood in the perimenopause.

Authors:  Peter J Schmidt; David R Rubinow
Journal:  Ann N Y Acad Sci       Date:  2009-10       Impact factor: 5.691

Review 9.  Cognition and mood in perimenopause: a systematic review and meta-analysis.

Authors:  Miriam T Weber; Pauline M Maki; Michael P McDermott
Journal:  J Steroid Biochem Mol Biol       Date:  2013-06-14       Impact factor: 4.292

10.  The menopause and hormone replacement therapy: views of women in general practice receiving hormone replacement therapy.

Authors:  P J Roberts
Journal:  Br J Gen Pract       Date:  1991-10       Impact factor: 5.386

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