| Literature DB >> 2880068 |
E G Walters, J M Tavaré, R M Denton, G Walters.
Abstract
Severe fasting hypoglycaemia developed in a patient with Hodgkin's disease after many courses of chemotherapy. Her serum contained a factor which stimulated glucose uptake by rat adipocytes, and this factor was found in the immunoglobulin fraction. The serum also displaced insulin bound to human erythrocytes and both precipitated and phosphorylated insulin receptors extracted from human placenta. The insulin-like substance is probably an antibody to the insulin receptor.Entities:
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Year: 1987 PMID： 2880068 DOI： 10.1016/s0140-6736(87)90064-x
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321