Literature DB >> 28799515

Antiepileptic Treatments in Developing Countries.

Jeremy Jost1, Athanase Millogo1,2, Pierre-Marie Preux1.   

Abstract

BACKGROUND: Epilepsy affects about 70 million people worldwide, nearly 90% of whom live in developing countries. Epilepsy is surrounded by myths and stigma in these countries. Discrimination and social stigmatization are difficult obstacles for patients to overcome. Knowledge, attitudes and practices towards epilepsy are often inadequate, even sometimes totally false and then dangerous.
METHODS: The goal was to present the situation and analyse the determinants of using antiepileptic drugs in developing countries.
RESULTS: The treatment gap exceeds 75% in most low-income countries, and could be even higher in rural areas. Reasons for that are low accessibility, availability, and/or affordability, lack of trained medical personnel and the associated beliefs and stigma. The interactions between drugs or due to other factors, such as malnutrition, are frequent. A long-lasting treatment is not usual for populations in developing countries due to cultural beliefs. The traditional healers are the first ones consulted in such a context, then delaying the entry in the "modern" medical care system.
CONCLUSION: Information and education campaigns are mandatory among the general population and among the medical and paramedical staff to make progress on the management of epilepsy in developing countries. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Epilepsy; antiepileptics drugs; developing countries; patients.; stigma; treatment gap

Mesh:

Substances:

Year:  2017        PMID: 28799515     DOI: 10.2174/1381612823666170809103202

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN: 1381-6128            Impact factor:   3.116


  3 in total

1.  Drosophila para bss Flies as a Screening Model for Traditional Medicine: Anticonvulsant Effects of Annona senegalensis.

Authors:  Samuel S Dare; Emiliano Merlo; Jesus Rodriguez Curt; Peter E Ekanem; Nan Hu; Jimena Berni
Journal:  Front Neurol       Date:  2021-01-13       Impact factor: 4.003

2.  Freedom From Seizures Might Be Key to Continuing Occupation After Epilepsy Surgery.

Authors:  Toshiki Nozaki; Ayataka Fujimoto; Tomohiro Yamazoe; Keiko Niimi; Shimpei Baba; Takamichi Yamamoto; Keishiro Sato; Hideo Enoki; Tohru Okanishi
Journal:  Front Neurol       Date:  2021-02-12       Impact factor: 4.003

3.  Availability, affordability, and quality of essential anti-seizure medication in Cambodia.

Authors:  Noudy Sengxeu; Chanraksmey Aon; Hanh Dufat; Farid Boumediene; Samleng Chan; Sina Ros; Pierre-Marie Preux; Voa Ratsimbazafy; Jeremy Jost
Journal:  Epilepsia Open       Date:  2021-06-23
  3 in total

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