Literature DB >> 28798241

Persisting fatigue and myalgia as the presenting features in a case of hypokalaemic periodic paralysis.

Matthew Thomas Neame1, David Wright2, Surendran Chandrasekaran2.   

Abstract

We report a case of a 9-year-old boy who developed hypokalaemic periodic paralysis (HypoPP) following a prodrome of persistent fatigue and muscle aches associated with mildly elevated creatine kinase (CK) levels.HypoPP is usually associated with a sudden onset of weakness and hypokalaemia at presentation. A review of published cases failed to identify any other reports of individuals with a similar onset of symptoms and elevated CK levels prior to the development of frank HypoPP.In the case described above, the association of these symptoms with elevated levels of CK may have been related to the underlying mutation in the skeletal muscle calcium channels that was subsequently identified.In cases of persisting fatigue and myalgia associated with elevated CK levels it may be helpful to consider HypoPP in the differential diagnosis. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  Muscle Disease; Paediatrics; Pain (neurology)

Mesh:

Substances:

Year:  2017        PMID: 28798241      PMCID: PMC5614135          DOI: 10.1136/bcr-2017-219991

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  2 in total

1.  The expanding phenotype of hypokalemic periodic paralysis in a Japanese family with p.Val876Glu mutation in CACNA1S.

Authors:  Mari Kurokawa; Michiko Torio; Kazuhiro Ohkubo; Vlad Tocan; Noriko Ohyama; Naoko Toda; Kanako Ishii; Kei Nishiyama; Yuichi Mushimoto; Ryuichi Sakamoto; Maki Nakaza; Riho Horie; Tomoya Kubota; Masanori P Takahashi; Yasunari Sakai; Masatoshi Nomura; Shouichi Ohga
Journal:  Mol Genet Genomic Med       Date:  2020-02-27       Impact factor: 2.183

2.  Reversible Severe Rhabdomyolysis Associated with Thyrotoxic Hypokalemic Periodic Paralysis.

Authors:  Praewchompoo Sathirapanya; Komsai Suwanno; Pornchai Sathirapanya
Journal:  Case Rep Neurol       Date:  2021-06-16
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.