Literature DB >> 28797874

Factors affecting articular cartilage repair after open-wedge high tibial osteotomy.

Chang-Wan Kim1, Seung-Suk Seo2, Chang-Rack Lee3, Heui-Chul Gwak1, Jung-Han Kim1, Sun-Gyu Jung1.   

Abstract

BACKGROUND: To evaluate the factors that affect articular cartilage repair after open-wedge high tibial osteotomy (OWHTO) and the relationship between regeneration of articular cartilage repair and clinical outcomes.
METHODS: Among the cases of OWHTO that were performed from March 2005 to February 2012, the patients who followed up for >2years and received a second-look arthroscopy were retrospectively reviewed. For clinical evaluation, the Knee Society scores and Western Ontario and McMaster Universities Osteoarthritis Index score were measured. For radiologic evaluation, the Kellgren-Lawrence scale, mechanical femorotibial angle, and joint line obliquity were used. In the initial and second-look arthroscopy, the status of the articular cartilage of the medial compartment was evaluated.
RESULTS: A total of 62 knees (61 patients) were included in this study. Articular cartilage repair was observed in 18 knees (29.0%). In multiple logistic regression analysis, patients with Kellgren-Lawrence Grade 4 (OR 0.076; 95% CI 0.007-0.822; P=0.034), the existence of a bipolar lesion (OR 0.108; 95% CI 0.016-0.724; P=0.022), or joint line obliquity >5° (OR 0.109; 95% CI 0.013-0.936; P=0.043) had significantly lower odds of articular cartilage repair compared to the corresponding counter group. In a comparison of clinical outcomes between a group that had articular cartilage repair and a group without repair, no significant difference was observed (P>0.05).
CONCLUSIONS: Severe arthrosis, existence of a bipolar lesion, and marked postoperative joint line obliquity had a negative impact on articular cartilage repair after OWHTO. However, articular cartilage repair showed unknown clinical significance.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Articular cartilage; Open-wedge high tibial osteotomy; Repair; Second-look arthroscopy

Mesh:

Year:  2017        PMID: 28797874     DOI: 10.1016/j.knee.2017.06.001

Source DB:  PubMed          Journal:  Knee        ISSN: 0968-0160            Impact factor:   2.199


  6 in total

1.  Allogeneic umbilical cord blood-derived mesenchymal stem cells combined with high tibial osteotomy: a retrospective study on safety and early results.

Authors:  Young-Woo Chung; Hong-Yeol Yang; Sung-Ju Kang; Eun-Kyoo Song; Jong-Keun Seon
Journal:  Int Orthop       Date:  2020-10-17       Impact factor: 3.075

2.  Risk factors and preventive strategy for excessive coronal inclination of tibial plateau following medial opening-wedge high tibial osteotomy.

Authors:  Sueen Sohn; In Jun Koh; Man Soo Kim; Yong In
Journal:  Arch Orthop Trauma Surg       Date:  2020-11-01       Impact factor: 3.067

Review 3.  Cartilage Restoration for Tibiofemoral Bipolar Lesions Results in Promising Failure Rates: A Systematic Review.

Authors:  Anirudh K Gowd; Alexander E Weimer; Danielle E Rider; Edward C Beck; Avinesh Agarwalla; Lisa K O'Brien; Michael J Alaia; Cristin M Ferguson; Brian R Waterman
Journal:  Arthrosc Sports Med Rehabil       Date:  2021-06-24

4.  The influence of post-operative knee coronal alignment parameters on long-term patient-reported outcomes after closed-wedge high tibial osteotomy.

Authors:  Norio Goto; Yukio Akasaki; Ken Okazaki; Umito Kuwashima; Kenyu Iwasaki; Hideya Kawamura; Hideki Mizu-Uchi; Satoshi Hamai; Hidetoshi Tsushima; Shinya Kawahara; Yasuharu Nakashima
Journal:  J Orthop       Date:  2020-01-29

5.  Chinese Clinical Practice Guidelines in Treating Knee Osteoarthritis by Periarticular Knee Osteotomy.

Authors:  Xin-Long Ma; Yong-Cheng Hu; Kun-Zheng Wang
Journal:  Orthop Surg       Date:  2022-05-04       Impact factor: 2.279

6.  Clinical benefit of high tibial osteotomy combined with the intervention of platelet-rich plasma for severe knee osteoarthritis.

Authors:  Conglei Dong; Chao Zhao; Fei Wang
Journal:  J Orthop Surg Res       Date:  2022-09-05       Impact factor: 2.677

  6 in total

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