C Neut1, S Mahieux1, L J Dubreuil2. 1. Inserm, U995, Lille inflammation research international center (LIRIC), university of Lille, 59006 Lille, France. 2. Inserm, U995, Lille inflammation research international center (LIRIC), university of Lille, 59006 Lille, France. Electronic address: luc.dubreuil@univ-lille2.fr.
Abstract
OBJECTIVE: The main goal of this study was to determine the in vitro susceptibility of strains collected from marketed probiotics to antibiotics used to treat community-acquired infections. METHODS: The minimum inhibitory concentrations (MICs) of 16 antibiotics were determined using a gradient strip (E test) or the agar dilution method for fidaxomicin. RESULTS: The probiotics demonstrated various antibiotic patterns. Bacterial probiotics are generally susceptible to most prescribed antibiotics orally administered, whereas yeast probiotics, such as Saccharomyces boulardii, are resistant. CONCLUSION: Special attention must be paid to co-prescriptions of antibiotics and probiotics to ensure that the probiotic strain is not susceptible.
OBJECTIVE: The main goal of this study was to determine the in vitro susceptibility of strains collected from marketed probiotics to antibiotics used to treat community-acquired infections. METHODS: The minimum inhibitory concentrations (MICs) of 16 antibiotics were determined using a gradient strip (E test) or the agar dilution method for fidaxomicin. RESULTS: The probiotics demonstrated various antibiotic patterns. Bacterial probiotics are generally susceptible to most prescribed antibiotics orally administered, whereas yeast probiotics, such as Saccharomyces boulardii, are resistant. CONCLUSION: Special attention must be paid to co-prescriptions of antibiotics and probiotics to ensure that the probiotic strain is not susceptible.
Authors: Grettel García-Collinot; Eduardo Osiris Madrigal-Santillán; Michel A Martínez-Bencomo; Rosa A Carranza-Muleiro; Luis J Jara; Olga Vera-Lastra; Daniel H Montes-Cortes; Gabriela Medina; María Pilar Cruz-Domínguez Journal: Dig Dis Sci Date: 2019-09-23 Impact factor: 3.199
Authors: Jaime Ramirez; Francisco Guarner; Luis Bustos Fernandez; Aldo Maruy; Vera Lucia Sdepanian; Henry Cohen Journal: Front Cell Infect Microbiol Date: 2020-11-24 Impact factor: 5.293