Associations Between Migraine and the Most Common Psychiatric Co-Morbidities.

PREMISE: Migraine is a common and potentially debilitating chronic neurologic disorder, with significant and clinically important psychiatric co-morbidities. PROBLEM: The individual and societal impact of migraine is both significant and diverse, and among these effects are a variety of psychiatric co-morbidities. Although the precise mechanisms underlying the relationships between migraine and psychiatric illness are not entirely clear, a variety of mood and anxiety disorders have not only been identified as co-prevalent in migraine, but have also been shown to impact migraine chronification. POTENTIAL SOLUTIONS: This review examines the recent literature investigating the associations between migraine and the most common psychiatric co-morbidities. Also discussed are implications for treating individuals with co-morbid migraine and psychiatric disorders, including recent innovations and improvements for the future.