Literature DB >> 28796082

The First Reported Case of Primary Intestinal-type Adenocarcinoma of the Middle Ear and Review of the Literature.

Marc-Elie Nader1, Diana Bell, Lawrence Ginsberg, Franco DeMonte, G Brandon Gunn, Paul W Gidley.   

Abstract

OBJECTIVE: Adenocarcinoma of the middle ear is a rare entity that must be distinguished from other adenomatous tumors of the temporal bone. We present the first patient of an intestinal-type adenocarcinoma originating from the middle ear. PATIENTS: A 58-year-old woman presented with an 8-year history of left otorrhea. Her middle ear effusions were quite thick and gummy. She underwent eight sets of pressure-equalization tubes within 3 years. In 2011, her physical examination identified a middle ear mass, and she underwent mastoidectomy. A middle ear adenoma was resected. She underwent an additional three mastoidectomies for recurrence, with pathology from the 4th mastoidectomy revealing a diagnosis of adenocarcinoma. Imaging, at that time, showed an extensive temporal bone and Eustachian tube tumor.
INTERVENTIONS: She underwent a left subtotal temporal bone resection, parotidectomy, infratemporal fossa resection, dural resection, and microvascular free flap reconstruction followed by postoperative proton beam radiotherapy. MAIN OUTCOME MEASURES: The final pathology report revealed intestinal-type adenocarcinoma.
RESULTS: Treatment was successful and the patient remains disease free 4 years later.
CONCLUSION: This is the first report of an intestinal-type adenocarcinoma of the middle ear and temporal bone. This patient also illustrates the difficulty of accurate histologic diagnosis of adenomatous tumors of the middle ear.

Entities:  

Mesh:

Year:  2017        PMID: 28796082     DOI: 10.1097/MAO.0000000000001541

Source DB:  PubMed          Journal:  Otol Neurotol        ISSN: 1531-7129            Impact factor:   2.311


  3 in total

Review 1.  Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone.

Authors:  Kelly R Magliocca; Esther X Vivas; Christopher C Griffith
Journal:  Head Neck Pathol       Date:  2018-08-01

Review 2.  Neuroendocrine Neoplasms of the Ear.

Authors:  Nora Katabi
Journal:  Head Neck Pathol       Date:  2018-08-01

3.  Middle ear adenomatous neuroendocrine tumors: suggestion for surgical strategy.

Authors:  Bingbin Xie; Shaorong Zhang; Chunfu Dai; Yuehui Liu
Journal:  Braz J Otorhinolaryngol       Date:  2020-06-15
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.