Dijana Varda Brkic1, Irina Pristas2, Ivan Cipris3, Marko Jelic2, Iva Butic2, Arjana Tambic Andrasevic2. 1. University Hospital Centre Zagreb, Department of Clinical Microbiology, 10000 Zagreb, Croatia. 2. University Hospital for Infectious Diseases, Department of Clinical Microbiology, 10000 Zagreb, Croatia. 3. Institute of Public Health County, Krapinsko-Zagorska, 49210 Zabok, Croatia.
Abstract
AIM: We report the first outbreak caused by Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae sequence type 258 (ST 258) clone that occurred in Croatia from May to December 2012. MATERIALS & METHODS: 23 carbapenem-resistant K. pneumoniae isolates were recovered from clinical and screening specimens of 12 patients hospitalized in a regional hospital. The first isolates from the 12 patients were typed using pulsed-field gel electrophoresis and multilocus sequence typing. RESULTS: PCR detection showed that all isolates harbored the bla KPC-2 gene, together with bla TEM-116 and bla SHV-11. CONCLUSION: The rapid detection of KPC-producing K. pneumoniae and vigorous implementation of infection control measures were necessary to successfully control the outbreak.
AIM: We report the first outbreak caused by Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae sequence type 258 (ST 258) clone that occurred in Croatia from May to December 2012. MATERIALS & METHODS: 23 carbapenem-resistant K. pneumoniae isolates were recovered from clinical and screening specimens of 12 patients hospitalized in a regional hospital. The first isolates from the 12 patients were typed using pulsed-field gel electrophoresis and multilocus sequence typing. RESULTS: PCR detection showed that all isolates harbored the bla KPC-2 gene, together with bla TEM-116 and bla SHV-11. CONCLUSION: The rapid detection of KPC-producing K. pneumoniae and vigorous implementation of infection control measures were necessary to successfully control the outbreak.
Authors: Alma Brolund; Nina Lagerqvist; Sara Byfors; Marc J Struelens; Dominique L Monnet; Barbara Albiger; Anke Kohlenberg Journal: Euro Surveill Date: 2019-02