Literature DB >> 28792293

The opioid epidemic: Challenges of sustained remission.

Nitin Chopra1, Lauren H Marasa2.   

Abstract

Opioid use disorder is a growing epidemic, with an alarming number of associated deaths. In 2014, in the United States, 18,893 lethal overdoses were related to prescription opioids and 10,574 due to heroin. Despite the growing number of treatment options for substance use disorders, which are chronic, relapsing-remitting conditions, relapse rates remain as high as 91%. In the United States, 7.5 million children reside with at least one patient who abuses drugs or alcohol. Mothers are twice as likely to lose custody of their children. They have higher rates of comorbid abuse and psychopathology and limited social supports. Child service agencies, commonly involved in these scenarios, are often pressured to find permanent placement for children, within an expedited timeframe, inconsistent with the need for sufficient time for recovery and goals of family inclusion and unity. We present the complicated case of a 25-year-old woman with a history of opioid use disorder and depression, who, after being in and out of treatment programs for years, had a lethal overdose. She had a significant family history of addiction and had lost custody of her children. This challenging, but common presentation draws attention to challenges in providing treatment during this opioid epidemic.

Entities:  

Keywords:  biopsychosocial; death; heroin; opioid; overdose; treatment

Mesh:

Substances:

Year:  2017        PMID: 28792293     DOI: 10.1177/0091217417720900

Source DB:  PubMed          Journal:  Int J Psychiatry Med        ISSN: 0091-2174            Impact factor:   1.210


  4 in total

Review 1.  Microglial Modulation as a Target for Chronic Pain: From the Bench to the Bedside and Back.

Authors:  Elena S Haight; Thomas E Forman; Stephanie A Cordonnier; Michelle L James; Vivianne L Tawfik
Journal:  Anesth Analg       Date:  2019-04       Impact factor: 5.108

2.  Machine Learning for Predicting Risk of Early Dropout in a Recovery Program for Opioid Use Disorder.

Authors:  Assaf Gottlieb; Andrea Yatsco; Christine Bakos-Block; James R Langabeer; Tiffany Champagne-Langabeer
Journal:  Healthcare (Basel)       Date:  2022-01-25

3.  Dietary Supplementation with Omega-3 Polyunsaturated Fatty Acids Reduces Opioid-Seeking Behaviors and Alters the Gut Microbiome.

Authors:  Joshua K Hakimian; Tien S Dong; Jorge A Barahona; Venu Lagishetty; Suchi Tiwari; Darien Azani; Matthew Barrera; Suhjin Lee; Amie L Severino; Nitish Mittal; Catherine M Cahill; Jonathan P Jacobs; Wendy M Walwyn
Journal:  Nutrients       Date:  2019-08-14       Impact factor: 5.717

4.  Alterations in microbiome composition and metabolic byproducts drive behavioral and transcriptional responses to morphine.

Authors:  Rebecca S Hofford; Nicholas L Mervosh; Tanner J Euston; Katherine R Meckel; Amon T Orr; Drew D Kiraly
Journal:  Neuropsychopharmacology       Date:  2021-06-14       Impact factor: 7.853

  4 in total

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