Literature DB >> 28792054

Droplet trapping and fast acoustic release in a multi-height device with steady-state flow.

Richard W Rambach1, Kevin Linder, Michael Heymann, Thomas Franke.   

Abstract

We demonstrate a novel multilayer polydimethylsiloxane (PDMS) device for selective storage and release of single emulsion droplets. Drops are captured in a microchannel cavity and can be released on-demand through a triggered surface acoustic wave pulse. The surface acoustic wave (SAW) is excited by a tapered interdigital transducer (TIDT) deposited on a piezoelectric lithium niobate (LiNbO3) substrate and inverts the pressure difference across the cavity trap to push a drop out of the trap and back into the main flow channel. Droplet capture and release does not require a flow rate change, flow interruption, flow inversion or valve action and can be achieved in as fast as 20 ms. This allows both on-demand droplet capture for analysis and monitoring over arbitrary time scales, and continuous device operation with a high droplet rate of 620 drops per s. We hence decouple long-term droplet interrogation from other operations on the chip. This will ease integration with other microfluidic droplet operations and functional components.

Entities:  

Year:  2017        PMID: 28792054     DOI: 10.1039/c7lc00378a

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  7 in total

1.  Microfluidic on-demand droplet generation, storage, retrieval, and merging for single-cell pairing.

Authors:  Hesam Babahosseini; Tom Misteli; Don L DeVoe
Journal:  Lab Chip       Date:  2019-01-29       Impact factor: 6.799

2.  An acoustofluidic platform for non-contact trapping of cell-laden hydrogel droplets compatible with optical microscopy.

Authors:  Anna Fornell; Carl Johannesson; Sean S Searle; Axel Happstadius; Johan Nilsson; Maria Tenje
Journal:  Biomicrofluidics       Date:  2019-07-11       Impact factor: 2.800

3.  A programmable microfluidic platform for multisample injection, discretization, and droplet manipulation.

Authors:  Hesam Babahosseini; Supriya Padmanabhan; Tom Misteli; Don L DeVoe
Journal:  Biomicrofluidics       Date:  2020-02-05       Impact factor: 2.800

Review 4.  Microfluidics: Innovations in Materials and Their Fabrication and Functionalization.

Authors:  Jacob B Nielsen; Robert L Hanson; Haifa M Almughamsi; Chao Pang; Taylor R Fish; Adam T Woolley
Journal:  Anal Chem       Date:  2019-12-02       Impact factor: 6.986

Review 5.  Recent advances in acoustic microfluidics and its exemplary applications.

Authors:  Yue Li; Shuxiang Cai; Honglin Shen; Yibao Chen; Zhixing Ge; Wenguang Yang
Journal:  Biomicrofluidics       Date:  2022-06-13       Impact factor: 3.258

6.  A Handy Liquid Metal Based Non-Invasive Electrophoretic Particle Microtrap.

Authors:  Lu Tian; Lunjia Zhang; Meng Gao; Zhongshan Deng; Lin Gui
Journal:  Micromachines (Basel)       Date:  2018-05-07       Impact factor: 2.891

7.  Trapping a moving droplet train by bubble guidance in microfluidic networks.

Authors:  Longxiang Zhang; Zhaomiao Liu; Yan Pang; Xiang Wang; Mengqi Li; Yanlin Ren
Journal:  RSC Adv       Date:  2018-02-27       Impact factor: 4.036

  7 in total

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