Literature DB >> 28791621

Assessment of dyssynchrony by gated myocardial perfusion imaging does not improve patient management.

Ran Lee1, Ravi V Shah2, Venkatesh L Murthy3.   

Abstract

Clinical trials have demonstrated improved outcomes with cardiac resynchronization therapy in patients with heart failure and electrical evidence of dyssynchrony. There has been intense effort at developing imaging markers of dyssynchrony with the aim of improved risk stratification. However, these efforts have not been fruitful to date. This article discusses mechanisms of cardiac dyssynchrony, reviews clinical data supporting resynchronization therapy, and addresses the lack of convincing evidence to support the use of noninvasive imaging measures of dyssynchrony in improving patient management.

Entities:  

Keywords:  Cardiac resynchronization therapy; Cardiomyopathy; Dyssynchrony; Dyssynchrony imaging; Heart failure

Mesh：

Year:  2017        PMID： 28791621      PMCID： PMC6312556          DOI： 10.1007/s12350-017-1022-9

Source DB:  PubMed          Journal:  J Nucl Cardiol        ISSN： 1071-3581            Impact factor:   5.952


  36 in total

1.  Effect of alteration of left ventricular activation sequence on the left ventricular end-systolic pressure-volume relation in closed-chest dogs.

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Journal:  Circ Res       Date:  1985-11       Impact factor: 17.367

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Journal:  Can J Cardiol       Date:  2007-03-15       Impact factor: 5.223

4.  Left bundle-branch block is associated with increased 1-year sudden and total mortality rate in 5517 outpatients with congestive heart failure: a report from the Italian network on congestive heart failure.

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5.  Results of the Predictors of Response to CRT (PROSPECT) trial.

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Journal:  Circulation       Date:  2008-05-05       Impact factor: 29.690

6.  Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial.

Authors:  James B Young; William T Abraham; Andrew L Smith; Angel R Leon; Randy Lieberman; Bruce Wilkoff; Robert C Canby; John S Schroeder; L Bing Liem; Shelley Hall; Kevin Wheelan
Journal:  JAMA       Date:  2003-05-28       Impact factor: 56.272

7.  Limitation of exercise tolerance in chronic heart failure: distinct effects of left bundle-branch block and coronary artery disease.

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Journal:  J Am Coll Cardiol       Date:  2004-05-05       Impact factor: 24.094

8.  Mechanistic features associated with improvement in mitral regurgitation after cardiac resynchronization therapy and their relation to long-term patient outcome.

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Journal:  Circ Heart Fail       Date:  2013-06-03       Impact factor: 8.790

9.  Phase analysis of gated myocardial perfusion single-photon emission computed tomography compared with tissue Doppler imaging for the assessment of left ventricular dyssynchrony.

Authors:  Maureen M Henneman; Ji Chen; Claudia Ypenburg; Petra Dibbets; Gabe B Bleeker; Eric Boersma; Marcel P Stokkel; Ernst E van der Wall; Ernest V Garcia; Jeroen J Bax
Journal:  J Am Coll Cardiol       Date:  2007-04-05       Impact factor: 24.094

10.  Prevention of disease progression by cardiac resynchronization therapy in patients with asymptomatic or mildly symptomatic left ventricular dysfunction: insights from the European cohort of the REVERSE (Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction) trial.

Authors:  Claude Daubert; Michael R Gold; William T Abraham; Stefano Ghio; Christian Hassager; Grahame Goode; Tamás Szili-Török; Cecilia Linde
Journal:  J Am Coll Cardiol       Date:  2009-10-01       Impact factor: 24.094
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  3 in total

1.  Impact of residual subtraction on myocardial blood flow and reserve estimates from rapid dynamic PET protocols.

Authors:  Edward P Ficaro; Venkatesh L Murthy; Alexis Poitrasson-Rivière; Jonathan B Moody; Jennifer M Renaud; Tomoe Hagio; Liliana Arida-Moody; Christopher Buckley; Richard L Weinberg
Journal:  J Nucl Cardiol       Date:  2021-11-15       Impact factor: 3.872

2.  Optimizing accuracy and precision with motion correction of PET myocardial blood flow measurements.

Authors:  Alexis Poitrasson-Rivière; Venkatesh L Murthy
Journal:  J Nucl Cardiol       Date:  2019-10-23       Impact factor: 5.952

3.  Deriving myocardial blood flow reserve from perfusion datasets: Dream or reality?

Authors:  Alexis Poitrasson-Rivière; Venkatesh L Murthy
Journal:  J Nucl Cardiol       Date:  2021-01-13       Impact factor: 5.952
  3 in total

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