Literature DB >> 28790645

HIV PATHOGENESIS-EMERGING CONCEPTS.

R N Misra1, A K Praharaj2, Yogesh Chander2.   

Abstract

CD4 receptor molecules on 'T' lymphocytes and macrophages have already been identified as the route of entry for HIV. However CCR5 and CXCR4 are identified only recently as the second receptors for HIV on macrophages and 'T' lymphocytes respectively. Presence of homozygous CCR5 Δ 32, a defective CCR5 gene leads to resistance to HIV infection in the risk groups. While heterozygous CCRS Δ 32 leads to delay in the progress of HIV infection to AIDS.

Entities:  

Keywords:  CCR5; CXCR4; HIV; SDF-1

Year:  2017        PMID： 28790645      PMCID： PMC5531965          DOI： 10.1016/S0377-1237(17)30092-8

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN： 0377-1237


  14 in total

1.  Identification of a major co-receptor for primary isolates of HIV-1.

Authors:  H Deng; R Liu; W Ellmeier; S Choe; D Unutmaz; M Burkhart; P Di Marzio; S Marmon; R E Sutton; C M Hill; C B Davis; S C Peiper; T J Schall; D R Littman; N R Landau
Journal:  Nature       Date:  1996-06-20       Impact factor: 49.962

2.  HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5.

Authors:  T Dragic; V Litwin; G P Allaway; S R Martin; Y Huang; K A Nagashima; C Cayanan; P J Maddon; R A Koup; J P Moore; W A Paxton
Journal:  Nature       Date:  1996-06-20       Impact factor: 49.962

Review 3.  Acute human immunodeficiency virus type 1 infection.

Authors:  J O Kahn; B D Walker
Journal:  N Engl J Med       Date:  1998-07-02       Impact factor: 91.245

4.  Chemokine receptors and genetic variability: another leap in HIV research.

Authors:  T R O'Brien; J J Goedert
Journal:  JAMA       Date:  1998-01-28       Impact factor: 56.272

5.  The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates.

Authors:  H Choe; M Farzan; Y Sun; N Sullivan; B Rollins; P D Ponath; L Wu; C R Mackay; G LaRosa; W Newman; N Gerard; C Gerard; J Sodroski
Journal:  Cell       Date:  1996-06-28       Impact factor: 41.582

6.  Chemokines: leucocyte recruitment and activation cytokines.

Authors:  D H Adams; A R Lloyd
Journal:  Lancet       Date:  1997-02-15       Impact factor: 79.321

7.  HIV-1 infection in a man homozygous for CCR5 delta 32.

Authors:  T R O'Brien; C Winkler; M Dean; J A Nelson; M Carrington; N L Michael; G C White
Journal:  Lancet       Date:  1997-04-26       Impact factor: 79.321

8.  CCR5 chemokine receptor variant in HIV-1 mother-to-child transmission and disease progression in children. French Pediatric HIV Infection Study Group.

Authors:  M Misrahi; J P Teglas; N N'Go; M Burgard; M J Mayaux; C Rouzioux; J F Delfraissy; S Blanche
Journal:  JAMA       Date:  1998-01-28       Impact factor: 56.272

9.  A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors.

Authors:  B J Doranz; J Rucker; Y Yi; R J Smyth; M Samson; S C Peiper; M Parmentier; R G Collman; R W Doms
Journal:  Cell       Date:  1996-06-28       Impact factor: 41.582

10.  Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.

Authors:  M Samson; F Libert; B J Doranz; J Rucker; C Liesnard; C M Farber; S Saragosti; C Lapoumeroulie; J Cognaux; C Forceille; G Muyldermans; C Verhofstede; G Burtonboy; M Georges; T Imai; S Rana; Y Yi; R J Smyth; R G Collman; R W Doms; G Vassart; M Parmentier
Journal:  Nature       Date:  1996-08-22       Impact factor: 49.962
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.