Literature DB >> 28790642

MID-TRIMESTER MTP USING ENDOCERVICAL PGE2 GEL AND SERIAL INTRAMUSCULAR CARBOPROST.

B K Goyal1, Gurneesh Singh2.   

Abstract

60 cases of mid-trimester pregnancy were terminated using endocervical PGE2 gel (for achieving cervical priming) followed by serial intramuscular injections of carboprost. In this prospective study, 56 cases were multiparae with gestational age varying between 15-22 weeks. The induction-abortion-interval was 8.4h ± 0.8h with a success rate of 100%. The incidence of incomplete abortion was 5% and check curettage was performed in 16.6% cases. Gastrointestinal side effects were common. Vomiting occurred in 42% cases and diarrhoea in 50%. Febrile morbidity was seen in 8.3% cases. There were no complications of the procedure. The method was highly acceptable to the patients being non-invasive and allowing ambulation throughout. This method of elective mid-trimester abortion is an effective alternative to the other commonly used methods like extra-amniotic ethacridine lactate or intra-amniotic hypertonic saline instillation.

Entities:  

Keywords:  Carboprost; Mid-trimester abortion; PGE2

Year:  2017        PMID: 28790642      PMCID: PMC5531953          DOI: 10.1016/S0377-1237(17)30088-6

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  10 in total

1.  Intra-amniotic urea as a midtrimester abortifacient: clinical results and serum and urinary changes.

Authors:  L S Burnett; T M King; M F Atienza; W R Bell
Journal:  Am J Obstet Gynecol       Date:  1975-01-01       Impact factor: 8.661

2.  Prostaglandin E2 vaginal suppository as a midtrimester abortifacient.

Authors:  R J Bolognese; S L Corson
Journal:  Am J Obstet Gynecol       Date:  1974-09-15       Impact factor: 8.661

3.  Abortifacient efficacy of intravaginal prostaglandin F2 .

Authors:  A C Wentz; K Austin; T M King
Journal:  Am J Obstet Gynecol       Date:  1973-01-01       Impact factor: 8.661

Review 4.  Artificial abortion at midpregnancy by mechanical stimulation of the uterus. A review of 20 years' experience with current methods in Japan.

Authors:  Y Manabe
Journal:  Am J Obstet Gynecol       Date:  1969-09-01       Impact factor: 8.661

5.  Mid-trimester abortion using prostaglandin E2 gel.

Authors:  Y Herabutya; N Israngura Na Ayudthaya
Journal:  Int J Gynaecol Obstet       Date:  1991-02       Impact factor: 3.561

6.  Midtrimester abortion by hypertonic saline instillation experience in Ramathibodi Hospital.

Authors:  S Suthutvoravut; V Supacharapongkul; S Bhiromswasdi
Journal:  J Med Assoc Thai       Date:  1983-03

7.  Action of prostaglandin in the pregnant woman.

Authors:  S Karim
Journal:  Ann N Y Acad Sci       Date:  1971-04-30       Impact factor: 5.691

8.  Prostaglandins and abortion. II. Single extra-amniotic administration of 0.92 mg. of 15-methyl prostaglandin F2alpha in Hyskon for termination of pregnancies in weeks 10 to 20 of gestation: an international multicenter study. World Health Organization Task Force on the Use of Prostaglandins for the Regulation of Fertility.

Authors: 
Journal:  Am J Obstet Gynecol       Date:  1977-11-15       Impact factor: 8.661

9.  Second-trimester abortion by intramuscular 15-methyl-prostaglandin F2 alpha or intravaginal prostaglandin E2 suppositories: a randomized trial.

Authors:  A F Borgida; J F Rodis; W Hanlon; A Craffey; L Ciarleglio; W A Campbell
Journal:  Obstet Gynecol       Date:  1995-05       Impact factor: 7.661

10.  Comparison of prostaglandin and hypertonic saline for termination of pregnancy.

Authors:  M Bygdeman
Journal:  Obstet Gynecol       Date:  1978-10       Impact factor: 7.661

  10 in total

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