| Literature DB >> 28790642 |
Abstract
60 cases of mid-trimester pregnancy were terminated using endocervical PGE2 gel (for achieving cervical priming) followed by serial intramuscular injections of carboprost. In this prospective study, 56 cases were multiparae with gestational age varying between 15-22 weeks. The induction-abortion-interval was 8.4h ± 0.8h with a success rate of 100%. The incidence of incomplete abortion was 5% and check curettage was performed in 16.6% cases. Gastrointestinal side effects were common. Vomiting occurred in 42% cases and diarrhoea in 50%. Febrile morbidity was seen in 8.3% cases. There were no complications of the procedure. The method was highly acceptable to the patients being non-invasive and allowing ambulation throughout. This method of elective mid-trimester abortion is an effective alternative to the other commonly used methods like extra-amniotic ethacridine lactate or intra-amniotic hypertonic saline instillation.Entities:
Keywords: Carboprost; Mid-trimester abortion; PGE2
Year: 2017 PMID: 28790642 PMCID: PMC5531953 DOI: 10.1016/S0377-1237(17)30088-6
Source DB: PubMed Journal: Med J Armed Forces India ISSN: 0377-1237