| Literature DB >> 2878838 |
P Virutamasen, C Wongsrichanalai, P Tangkeo, Y Nitichai, D Rienprayoon.
Abstract
Oral glucose tolerance test and determination of insulin, cholesterol, triglycerides, total bilirubin, serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), alkaline phosphatase and cortisol in blood were performed on 57 Thai women who had used depot-medroxyprogesterone acetate (DMPA) for 5 years or more and 24 healthy non-DMPA users. Plasma insulin, alkaline phosphatase and morning cortisol levels were significantly higher in the DMPA users than in the non-users. There were no significant differences for other laboratory tests. The findings suggest some effects of DMPA on carbohydrate metabolism and liver function in long-term users.Entities:
Keywords: Adrenal Cortex Hormones; Asia; Biology; Carbohydrate Metabolic Effects; Cholesterol; Contraception; Contraceptive Agents, Female; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--side effects; Contraceptive Methods; Demographic Factors; Developing Countries; Diseases; Endocrine System; Family Planning; Glucose Metabolism Effects; Glucose Tolerance Test; Hepatic Effects; Hormones; Injectables; Laboratory Procedures; Lipid Metabolic Effects; Lipids; Liver Dysfunction; Longterm Effects; Medroxyprogesterone Acetate--side effects; Metabolic Effects; Physiology; Population; Population Dynamics; Research Report; Southeastern Asia; Thailand; Time Factors
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Year: 1986 PMID： 2878838 DOI： 10.1016/0020-7292(86)90086-x
Source DB: PubMed Journal: Int J Gynaecol Obstet ISSN： 0020-7292 Impact factor: 3.561