| Literature DB >> 28787585 |
Patrick L Ferree1, Stefano Di Talia2.
Abstract
Early embryonic development is characterized by rapid cleavage divisions, which impose significant constraints on metabolic pathways. In this issue, Song et al. (2017) show that Drosophila embryos synthesize a large fraction of nucleotides on the go and that negative feedback between dATP and ribonucleotide reductase ensures tight control of dNTP concentration.Entities:
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Year: 2017 PMID： 28787585 DOI： 10.1016/j.devcel.2017.07.016
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270