BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory disease presenting in intertriginous areas. HS is associated with a number of disease-modifying comorbidities, including metabolic syndrome and androgen dysfunction, and smoking. OBJECTIVE: This review provides a synopsis of the aetiology and diagnosis of HS, and an overview of management for this often devastating disease. DISCUSSION: The clinical course and disease severity of HS are variable among patients. HS has profound physical and psychological consequences that affect patients' quality of life. Effective treatment is now a realistic goal, but needs to be combined with treatment of the comorbidities and psyche. Evidence-based management guidelines have been established for the management of this disease. General practitioners play a pivotal role in the holistic treatment of this disease.
BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease presenting in intertriginous areas. HS is associated with a number of disease-modifying comorbidities, including metabolic syndrome and androgen dysfunction, and smoking. OBJECTIVE: This review provides a synopsis of the aetiology and diagnosis of HS, and an overview of management for this often devastating disease. DISCUSSION: The clinical course and disease severity of HS are variable among patients. HS has profound physical and psychological consequences that affect patients' quality of life. Effective treatment is now a realistic goal, but needs to be combined with treatment of the comorbidities and psyche. Evidence-based management guidelines have been established for the management of this disease. General practitioners play a pivotal role in the holistic treatment of this disease.
Authors: Vishnu Hosur; Daniel A Skelly; Christopher Francis; Benjamin E Low; Vivek Kohar; Lisa M Burzenski; Mansoor M Amiji; Leonard D Shultz; Michael V Wiles Journal: Drug Discov Today Date: 2020-05-05 Impact factor: 7.851
Authors: Kinnor Das; Steven Daveluy; George Kroumpouzos; Komal Agarwal; Indrashis Podder; Katherine Farnbach; Alex G Ortega-Loayza; Jacek C Szepietowski; Stephan Grabbe; Mohamad Goldust Journal: J Clin Med Date: 2022-01-27 Impact factor: 4.241