BACKGROUND AND PURPOSE: Understanding fall risk factors in people with mild cognitive impairment (MCI) and Alzheimer disease (AD) can help to establish specific plans for prevention of falls. The purpose of this study was to identify fall risk factors in older adults with MCI and mild AD. METHODS: A prospective study was conducted with community-dwelling older adults (40 MCI; 38 mild AD). The assessments consisted of sociodemographic and health variables, caloric expenditure, functional status, functional mobility (10-m walk test, dual-task test, and transition Timed Up and Go phases), cognitive domains, and depressive symptoms. Falls were recorded for 6 months by a falls calendar and monthly telephone calls. RESULTS: Falls were reported in 52.6% and 51.4% of people with MCI and mild AD, respectively. Among people with MCI, lower functional status, higher time spent on walk and dual task tests, and higher depressive symptom scores were associated with falls. Higher time spent on the dual-task test was independently associated with falls. Among people with mild AD, falls were associated with lower time spent on the walk test and turn-to-sit phase, and a higher visuospatial domain score. Lower time spent on the turn-to-sit phase was identified as an independent predictor of falls. CONCLUSIONS: Careful attention should be given to dual-task and turn-to-sit activities when detecting risk of falls among older people with MCI and mild AD.
BACKGROUND AND PURPOSE: Understanding fall risk factors in people with mild cognitive impairment (MCI) and Alzheimer disease (AD) can help to establish specific plans for prevention of falls. The purpose of this study was to identify fall risk factors in older adults with MCI and mild AD. METHODS: A prospective study was conducted with community-dwelling older adults (40 MCI; 38 mild AD). The assessments consisted of sociodemographic and health variables, caloric expenditure, functional status, functional mobility (10-m walk test, dual-task test, and transition Timed Up and Go phases), cognitive domains, and depressive symptoms. Falls were recorded for 6 months by a falls calendar and monthly telephone calls. RESULTS:Falls were reported in 52.6% and 51.4% of people with MCI and mild AD, respectively. Among people with MCI, lower functional status, higher time spent on walk and dual task tests, and higher depressive symptom scores were associated with falls. Higher time spent on the dual-task test was independently associated with falls. Among people with mild AD, falls were associated with lower time spent on the walk test and turn-to-sit phase, and a higher visuospatial domain score. Lower time spent on the turn-to-sit phase was identified as an independent predictor of falls. CONCLUSIONS: Careful attention should be given to dual-task and turn-to-sit activities when detecting risk of falls among older people with MCI and mild AD.
Authors: Thanwarat Chantanachai; Morag E Taylor; Stephen R Lord; Jasmine Menant; Kim Delbaere; Perminder S Sachdev; Nicole A Kochan; Henry Brodaty; Daina L Sturnieks Journal: PeerJ Date: 2022-05-30 Impact factor: 3.061
Authors: Claire E Adam; Annette L Fitzpatrick; Cindy S Leary; Anjum Hajat; Elizabeth A Phelan; Christina Park; Erin O Semmens Journal: Int J Environ Res Public Health Date: 2021-04-02 Impact factor: 3.390
Authors: Alex Baby Paul; Dakshin Sitaram Padmanabhan; Vineeth Suresh; Sunav Nellai Nayagam; Niveditha Kartha; George Paul; Priya Vijayakumar Journal: J Family Med Prim Care Date: 2022-03-18
Authors: Elissa Burton; Keith Hill; Kathryn A Ellis; Anne-Marie Hill; Meggen Lowry; Rachael Moorin; Joanne A McVeigh; Angela Jacques; Kirk I Erickson; Joel Tate; Sarah Bernard; Carolyn F Orr; Luke Bongiascia; Roger Clarnette; Melanie L Clark; Shannon Williams; Nicola Lautenschlager Journal: BMJ Open Date: 2022-04-18 Impact factor: 3.006
Authors: Rebecca J Kamil; Dara Bakar; Matthew Ehrenburg; Scott Frankenthaler; Eric X Wei; Eric Anson; Esther Oh; Yuri Agrawal Journal: Alzheimers Dement (N Y) Date: 2018-04-07
Authors: Rebecca M Bollinger; Audrey Keleman; Regina Thompson; Elizabeth Westerhaus; Anne M Fagan; Tammie Ls Benzinger; Suzanne E Schindler; Chengjie Xiong; David Balota; John C Morris; Beau M Ances; Susan L Stark Journal: BMJ Open Date: 2021-09-15 Impact factor: 2.692