PURPOSE: In the present study, we examined how the body mass index (BMI) affected the outcomes of laparoscopic fundoplication for GERD in patients, whose backgrounds were matched in a propensity score-matched analysis. METHODS: We divided the patients into two groups (BMI <25 kg/m2 and BMI ≥25 kg/m2). The following background information was matched for the propensity score-matched analysis: sex, age, degree of esophageal hiatal hernia, acid exposure time, and degree of reflux esophagitis. In total, 105 subjects were extracted in each group. The surgical outcomes and postoperative outcomes of patients with BMI <25 kg/m2 (Group A) and those with BMI ≥25 kg/m2 (Group B) were compared and examined. RESULTS: There were no differences in the surgical procedure, intraoperative complications, or estimated blood loss (p = 0.876, p = 0.516, p = 0.438, respectively); however, the operative time was significantly prolonged in Group B (p = 0.003). The rate of postoperative recurrence in Group A was 17% (15/87 patients), while that in Group B was 11% (12/91 patients), and did not differ to a statistically significant extent (p = 0.533). CONCLUSIONS: Although the operative time for GERD in obese patients was prolonged in comparison with non-obese patients, there was no difference in the rate of postoperative recurrence.
PURPOSE: In the present study, we examined how the body mass index (BMI) affected the outcomes of laparoscopic fundoplication for GERD in patients, whose backgrounds were matched in a propensity score-matched analysis. METHODS: We divided the patients into two groups (BMI <25 kg/m2 and BMI ≥25 kg/m2). The following background information was matched for the propensity score-matched analysis: sex, age, degree of esophageal hiatal hernia, acid exposure time, and degree of reflux esophagitis. In total, 105 subjects were extracted in each group. The surgical outcomes and postoperative outcomes of patients with BMI <25 kg/m2 (Group A) and those with BMI ≥25 kg/m2 (Group B) were compared and examined. RESULTS: There were no differences in the surgical procedure, intraoperative complications, or estimated blood loss (p = 0.876, p = 0.516, p = 0.438, respectively); however, the operative time was significantly prolonged in Group B (p = 0.003). The rate of postoperative recurrence in Group A was 17% (15/87 patients), while that in Group B was 11% (12/91 patients), and did not differ to a statistically significant extent (p = 0.533). CONCLUSIONS: Although the operative time for GERD in obesepatients was prolonged in comparison with non-obesepatients, there was no difference in the rate of postoperative recurrence.
Entities:
Keywords:
Body mass index (BMI); Gastro-esophageal reflux disease (GERD); Laparoscopic fundoplication; Propensity score matching; Surgical outcomes
Authors: Jacob A Chisholm; Glyn G Jamieson; Carolyn J Lally; Peter G Devitt; Philip A Game; David I Watson Journal: J Gastrointest Surg Date: 2009-03-04 Impact factor: 3.452